Handbook of Cannabis and Related Pathologies

Biology, Pharmacology, Diagnosis, and Treatment
Erscheinungsjahr 2017
ISBN: 978-0-12-800756-3
Verlag: William Andrew Publishing

Buch, Englisch, 1170 Seiten, Format (B × H): 216 mm x 276 mm, Gewicht: 3330 g

Handbook of Cannabis and Related Pathologies: Biology, Pharmacology, Diagnosis, and Treatment is the first book to take an interdisciplinary approach to the understanding of cannabis use and misuse. Recent worldwide trends toward decriminalizing marijuana for medical use have increased legal use of the drug and recreational use remains high, making cannabis one of the most commonly used drugs.

Cannabis has a wide range of adverse neurological effects, and use and abuse can lead to physical, social, and psychopathological issues that are multifarious and complex. Effective understanding and treatment requires knowledge of the drug’s effects from across scientific disciplines.

This book provides an overview of the biological and pharmacological components of the cannabis plant, outlines its neurological, social, and psychopathological effects, assists in the diagnosis and screening for use and dependency, and aids researchers in developing effective treatments for cannabis-related issues and disorders.

Fully illustrated, with contributions from internationally recognized experts, it is the go-to resource for neuroscientists, pharmacologists, pathologists, public-health workers, and any other researcher who needs an in-depth and cross-disciplinary understanding of cannabis and its effects.

Autoren/Hrsg.

Preedy, Victor R.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Public Health, Gesundheitsmanagement, Gesundheitsökonomie, Gesundheitspolitik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pathologie, Cytopathologie, Histopathologie
• Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Neurowissenschaften, Kognitionswissenschaft

Inhaltsverzeichnis

1. The Cannabis Plant: Botanical Aspects

2. The biosynthesis of cannabinoids 3. Increasing plant concentrations of THC and implications on health related disorders

3. Age as a Predictor of Cannabis Use

4. Lifetime cannabis use and cognition in psychosis spectrum disorders

5. A Profile of Synthetic Cannabinoid Users

6. Dual disorders in cannabis misuse

7. Cannabis use and cognitive function

8. Cannabis, migration and psychosis onset

9. The global epidemiology and disease burden of cannabis use and dependence

10. International aspects of cannabis use and misuse – the Australian perspective

11. International aspects of cannabis use and misuse: Egypt

12. Cannabis Body Packing – A Caribbean Perspective

13. Gender differences in cannabis use disorders

14. The role of age in the onset and further development of cannabis use disorders

15. Effects of Cannabis Use on Neurocognition in Adolescents and Emerging Adults with Psychiatric Comorbidities

16. Correlates and consequences of prenatal cannabis exposure (PCE): identifying and characterizing vulnerable maternal populations and determining outcomes for exposed offspring

17. Cannabis and clubbing: Relevance of cannabis and polydrug use in the clubbing culture today

18. Cannabis and Sexual Behavior

19. Friendships and Cannabis Use

20. Students’ knowledge of cannabis

21. Childhood trauma and cannabis - risk factors in severe mental disorders

22. Parent’s Influence on Their Children’s Cannabis Use

23. Cannabis Users and Premorbid Intellectual Quotient (IQ)

24. Cannabis and traffic accidents

25. Drug-related pictures, attentional bias, and cannabis use

26. Cannabis use and first-episode psychosis patients (FEP)

27. Cannabis, associative memory, fMRI, and the Implicit Association Test

28. Stress Response in Cannabis Users and Psychosis

29. Motivation in Chronic Cannabis Use

30. Cannabis use and its association to mental illness: a focus on mood and anxiety disorders

31. Cannabis Use and Well-being

32. Craving and cannabis: A potential paradox

33. Delta 9-tetrahydrocannabinol and catalepsy-like immobilization

34. The interactive nature of cannabis and schizophrenia risk genes

35. Neuroimaging findings in Adolescent Cannabis use and Early Phase Psychosis

36. Cannabis smoking in adult schizophrenia: A cognitive and functional magnetic resonance imaging perspective

37. The long-lasting effects of cannabis use on movement and brain regions that control movement

38. Assessment of cannabis acute effects on driving skills: laboratory, simulator and on road studies

39. Chronic cannabis use and axonal fibre connectivity

40. Microglial activation and cannabis exposure

41. Cannabis and psychosis: correlation, causality and consequences

42. Cannabis use and cannabis use disorders in bipolar disorder – causes and consequences

43. Cannabis use in epilepsy – risks and benefits

44. Cannabis, cannabinoids and visceral pain.

45. Cannabis and Post-Operative Analgesia

46. Chronic cannabis abuse and thyroid function

47. Cannabis Hyperemesis Syndrome

48. Cannabis and Cannabinoids and the effects on gastrointestinal function: an overview

49. Cardiovascular Effects of Cannabis Usage

50. Cannabis and Stroke

51. Cannabis Smoking and the Lung

52. Cannabis and hepatic injury

53. Cannabis allergy: more than a bad trip

54. Marijuana and Breastfeeding

55. Hypocretins/orexins and addiction: role in cannabinoid dependence

56. Regulatory role of cannabinoids for skin barrier functions and cutaneous inflammation

57. Cannabinoids and the Cannabinoid Receptors: An Overview

58. Signalling and Regulation of the Cannabinoid CB1 Receptor

59. Allosteric modulation of the Cannabinoid CB1 Receptor

60. The polymorphisms of the CB2 cannabinoid receptor

61. Chemistry of Cannabinoid Receptor Agonists

62. The endocannabinoid system as a target for new antiseizure drugs

63. Pharmacological aspects of anandamide and 2-arachidonoyglycerol as bioactive lipids

64. Pharmacological aspects of NMDA receptors

Über Autor(innen)

Preedy, Victor R.
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.