Buch, Englisch, 634 Seiten, Format (B × H): 216 mm x 276 mm, Gewicht: 2030 g
Buch, Englisch, 634 Seiten, Format (B × H): 216 mm x 276 mm, Gewicht: 2030 g
ISBN: 978-0-12-387829-8
Verlag: William Andrew Publishing
Zielgruppe
Primary: Academic, medical, and pharmaceutical researchers in bone biology, clinical genetics, rheumatology, endocrinology, osteology; Secondary: Clinicians who threat metabolic bone diseases and musculoskeletal disorders (endocrinologists, rheumatologists, osteologists) and offer genetic counseling.</p>
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Endokrinologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Rheumatologie, Muskelerkrankungen
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Pharmazie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik
Weitere Infos & Material
Part I: General Background to Bone Biology
1. Biology of Bone and Cartilage
Brendan Boyce, Michael Zuscik, Lianping Xing
2. Overview of Bone Structure and Strength
Mary L. Bouxsein
3. Overview of Joint and Cartilage Biology
Frank Luyten and Rik JU Lories
4. Integrating Endocrine and Paracrine Influences on Bone: Lessons from Parathyroid Hormone and Parathyroid Hormone-related Protein
T. John Martin and Natalie A. Sims
5. Energy Homeostasis and Neuronal Regulation of Bone Remodeling
Gerard Karsenty, Mathieu Ferron and Franck Oury
6. Neuropeptide Y and Bone Regulation
Paul A. Baldock
Part II: General Background to Genetics
7. Genome-wide Association Studies
Matthew Brown and Emma L. Duncan
8. Genomic Profiling in Bone
Gabriela G. Loots and Bryan D. Hudson
9. Copy Number Variation
Hong-Wen Deng, Tie-Lin Yang, Yan Guo and Christopher J. Papasian
10. Prospects of Gene Therapy
Brendan Lee, Merry ZC Ruan and Kilian Guse
11. Pharmacogentics and Pharmacogenomics of Osteoporosis: Personalized Medicine Outlook
Tuan V. Nguyen and John A. Eisman
12. Genetic Testing & Counselling
Ingrid A. Holm, Christina M. Jacobsen, Yiping Shen and Stephanie J. Brewster
13. Mouse models: Approaches to Generating in vivo Models for Hereditary Disorders of Mineral and Skeletal Homeostasis
Sian E. Piret and Rajesh V. Thakker
14. Fetal Control of Calcium and Phosphate Homeostasis - Lessons from Mouse Models
Christopher S. Kovacs
15. Control of Skeletal Homeostasis during Pregnancy and Lactation - Lessons from Physiological Models
Christopher S. Kovacs
Part III: Disorders of Bone and Joint
16. Osteogenesis Imperfecta
Joan Marini and M. Helen Rajpar
17. Osteoporosis Genes Identified by Genome-wide Association Studies
Andre Uitterlinden and Fernando Rivadenerira
18. Osteoarthritis - Genetic Studies of Monogenic and Complex Forms
Ana M. Valdes
19. Paget's Disease
Stuart H. Ralston and Omar M.E. Albagha
20. Heritable Disorders of RANKL, OPG, RANK and NF-KB Signalling
Michael Whyte
21. Skeletal Dysplasias
William G. Cole
22. Hypophosphatasia
Michael P. Whyte
23. Sclerosing Bone Disorders
Bram Perdu and Wim Van Hul
24. Fibrodysplasia (Myositis) Ossificans Progressiva
Andria L. Culbert, Salin A. Chakkalakal, Michael R. Convente, Vitali Y. Lounev, Frederick S. Kaplan and Eileen M. Shore
Part IV: Parathyroid and Related Disorders
25. Hyperparathyroidism
Andrew Arnold and Jessica Costa-Guda
26. Hypoparathyroidism
Rajesh V. Thakker
27. Gsa, Pseudohypoparathyroidism, Fibrous Dysplasia, and McCune-Albright Syndrome
Lee S. Weinstein, Allen M. Spiegel and Michael Collins
28. Genetic disorders affecting PTH/PTHrP receptor function
Harald Jueppner and Caroline Silve
29. Genetically Determined Disorders of the Calcium-Sensing Receptor
Edward M. Brown and Ogo I. Egbuna
30. Multiple Endocrine Neoplasia Type 1 (MEN1)
Rajesh V. Thakker
31. Multiple Endocrine Neoplasia Type 2 (MEN2)
Bruce Robinson, Rory Clifton-Bligh and Matti Gild
Part V: Vitamin D and Renal Disorders
32. Heritable Renal Phosphate Wasting Disorders
Marc K. Drezner
33. Genetic Disorders of Vitamin D Synthesis and Action
David Feldman, Peter Malloy and Walter L. Miller
34. Renal Fanconi Syndrome, Dent's Disease and Bartter's Syndrome
Olivier Devuyst and Takashi Igarashi
35. Inherited Magnesium Disorders
Scott J. Schurman, Dhruval Patel, Anil Singh and Steven J. Scheinman
36. Genetic Hypercalciuria: A Major Risk Factor in Kidney Stones
David Bushinsky and Orson W. Moe