8-Membered Heterocycle Synthesis

Erscheinungsjahr 2023
ISBN: 978-0-323-95652-9
Verlag: William Andrew Publishing

Buch, Englisch, 650 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 450 g

8-Membered Heterocycle Synthesis focuses on both the new and established methods for the synthesis of various 8-membered heterocycles. 8-membered heterocyclic compounds act as target molecules for a wide range of synthetic studies and are present in a broad range of natural products, showing a wide variety of pharmaceutical and biological properties. Covering an important and rapidly growing branch of heterocyclic chemistry, this book brings together every protocol for the synthesis of 8-membered heterocycles in one place, allowing the reader to see all the possibilities for making a particular compound using one particular reagent. 

Providing up-to-date and comprehensive information about the synthesis of medium-ring heterocycles and the latest information on this fast-moving field, with easy access to the synthetic protocols for different 8-membered heterocycles, case studies, and application, this book will be essential reading for students, pharmacologists, biochemists, organic and medicinal chemists, researchers, and academic professionals.

Fachgebiete

• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Pharmazeutische Technologie
• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
• Naturwissenschaften Chemie Organische Chemie Biochemie

Inhaltsverzeichnis

1. Synthesis of azocines
2. Synthesis of azocines by diene metathesis
3. Synthesis of azocines by ring-expansion
4. Synthesis of azocines and diazocines from amine containing alkenes and alkynes
5. Synthesis of diazocines
6. Synthesis of diazocines and oxocines by cyclization of dienes
7. Synthesis of diazocines and oxocines by ring-contraction and -expansion
8. Synthesis of azocines and oxocines by ring-closure of halo, amine and oxo compounds
9. Synthesis of oxocines
10. Synthesis of oxazocines
11. Synthesis of thiocines and thiazocines
References