Advances in Cancer Research

AEG-1/MTDH/Lyric Implicated in Multiple Human Cancers
Erscheinungsjahr 2013
ISBN: 978-0-12-401676-7
Verlag: William Andrew Publishing

Buch, Englisch, 264 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 530 g

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. This volume covers AEG-1/MTDH/Lyric implicated in multiple human cancers.

Zielgruppe

<p>Researchers and students in the basic and clinical sciences of cancer biology and oncology, plus related areas in genetics, immunology, pharmacology, cell biology, and molecular biology.</p>

Autoren/Hrsg.

Weitere Mitwirkende

Sarkar, Devanand

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie

Inhaltsverzeichnis

1. AEG-1/MTDH/LYRIC the Beginning: Initial Cloning, Structure, Expression Profile, and Regulation of Expression2. AEG-1/MTDH/LYRIC: Clinical Significance3. AEG-1/MTDH/LYRIC: Signaling Pathways, Downstream Genes, Interacting Proteins, and Regulation ofTumor Angiogenesis4. Pleiotropic Roles of Metadherin/AEG-1 in Breast Cancer5. Drug Resistance Mediated by MTDH/AEG-1/Lyric6. The Role of AEG-1/MTDH/LYRIC in the Pathogenesis of Central Nervous System Disease7. AEG-1/MTDH/LYRIC in Liver Cancer

Über Autor(innen)

Sarkar, Devanand
Dr. Sarkar received his MBBS from Dhaka Medical College, Bangladesh and PhD from Nagoya University, Japan. After postdoctoral training in Columbia University, NY he joined Virginia Commonwealth University (VCU) as a faculty where he is now a Professor in the Department of Human and Molecular Genetics, and Associate Director of Education and Training at Massey Cancer Center. Dr. Sarkar's research focuses on identifying novel regulators of hepatocellular carcinoma (HCC), especially obesity-induced HCC, and developing targeted gene- and immunotherapy based on the accrued knowledge. Dr. Sarkar has published more than 280 papers and his research is funded by NCI, NIDDK and DOD.