Volatile Biomarkers: Non-Invasive Diagnosis in Physiology and Medicine

Neuausgabe 2013
ISBN: 978-0-444-62613-4
Verlag: ELSEVIER

Buch, Englisch, 600 Seiten, Format (B × H): 197 mm x 241 mm, Gewicht: 1479 g

Volatile organic compounds (VOCs) in exhaled breath, sweat or urine carry much information on the state of human health. The role of VOCs in clinical diagnosis and therapeutic monitoring is expected to become increasingly significant due to recent advances in the field. Volatile Biomarkers: Non-Invasive Diagnosis in Physiology and Medicine includes the latest discoveries and applications for VOCs from the world's foremost scientists and clinicians working in this emerging analytic area.

Zielgruppe

chemists, biochemists, cell biologists, physiologists, and clinicians with an interest in breath analysis

Autoren/Hrsg.

Amann, Anton

Davis, Cristina

Smith, David

Beauchamp, Jonathan

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Biochemie (med.)
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Molekularbiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie
• Naturwissenschaften Biowissenschaften Zellbiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Pneumologie, Atmung, Asthma

Inhaltsverzeichnis

A: Interpretation of Breath Analysis Data 1. Mathematical and Statistical Approaches for Interpreting Biomarker Compounds in Exhaled Human Breath 2. Issues and Challenges in Human Breath Research: Perspectives from Our Experience
B: Real-Time Analysis of Exhaled Breath 3. Physiological Modeling for Analysis of Exhaled Breath
C: Physiological and Clinical Studies 4. Recent SIFT-MS Studies of Volatile Compounds in Physiology, Medicine and Cell Biology 5. The Analysis of Oral Air by Selected Ion Flow Tube Mass Spectrometry Using Indole and Methylindole as Examples 6. Smokers Breath as Seen by Proton-Transfer-Reaction Time-of-Flight Mass Spectrometry (PTR-TOF-MS) 7. Exhaled Breath Analysis in Occupational Medicine 8. Volatile Organic Compounds in Human Breath: Biogenic Origin and Point-of-Care Analysis
Approaches 9. Breath Analysis in Critically Ill Patients-Potential and Limitations 10. Analysis of Cancer Biomarkers in Exhaled Breath and Comparison with Sensory Indications by Dogs
D: Nitric Oxide, No, and Carbon Monoxide, Co 11. Added Value with Extended NO Analysis 12. Carbon Monoxide as an Exhaled Biomarker of Pulmonary Diseases 13. Exhaled Nitric Oxide in Clinical Practice: Recent Advances and New Challenges
E: Clinical Breath Tests 14. An Update on 13C-Breath Tests: The Transition to Acceptability into Clinical Practice
F: Development and Use Of Sensors 15. Sensors for Exhaled Gas Analysis: An Analytical Review 16. Arrays of Nanomaterial-Based Sensors for Breath Testing 17. Smart Sensor Systems for Human Health Breath Monitoring Applications 18. VOC Analysis by SIFT-MS, GC-MS, and Electronic Nose for Diagnosing and Monitoring Disease
G: Exhaled Breath Condensate (Ebc) And Particulates 19. Measurement of Biomarkers of Oxidative Stress and Airway Inflammation in Exhaled Breath Condensate: Methodology and Potential Applications in Patients with COPD and Healthy Smokers 20. Particles in Exhaled Air-A Novel Method of Sampling Non-Volatiles in Exhaled Air
H: Volatiles Of Microbial Origin: Urine, Stool and In Vitro Cultures 21. Challenges in the Investigation of Volatile Disease Biomarkers in Urine 22. Volatile Organic Compounds (VOCs) Found in Urine and Stool 23. Volatile Organic Compounds (VOCs) Released by Pathogenic Microorganisms in vitro: Potential Breath Biomarkers for Early-Stage Diagnosis of Disease
I: Urban Search and Rescue Operations 24. Potential Applications of Volatile Organic Compounds in Safety and Security

Über Autor(innen)

Beauchamp, Jonathan
Jonathan Beauchamp is manager of the Emissions Analytics and Diagnostics group at the Fraunhofer Institute for Process Engineering and Packaging IVV in Freising, Germany. He has been involved in academic and industrial breath research for the past 15 years and is currently principal investigator in several breath-related projects. He is an active member and current treasurer of the International Association of Breath Research (IABR).

Davis, Cristina
Cristina Davis is chair and professor of Mechanical and Aerospace Engineering at the University of California Davis, United States. Her research focuses on development of novel chemical and biological sensor systems and biomarker identification in agriculture and human/animal health monitoring. She has 12 issued patents and has coauthored over 100 peer-reviewed journal articles and book chapters. She is current chair-elect of IABR.