E-Book, Englisch, 326 Seiten, Format (B × H): 191 mm x 235 mm
Apte Liver Regeneration
1. Auflage 2015
ISBN: 978-0-12-800431-9
Verlag: William Andrew Publishing
Format: EPUB
Kopierschutz: 6 - ePub Watermark
Basic Mechanisms, Relevant Models and Clinical Applications
E-Book, Englisch, 326 Seiten, Format (B × H): 191 mm x 235 mm
ISBN: 978-0-12-800431-9
Verlag: William Andrew Publishing
Format: EPUB
Kopierschutz: 6 - ePub Watermark
Liver Regeneration: Basic Mechanisms, Relevant Models and Clinical Applications presents cutting-edge information on liver regeneration research through an integrated, systems-wide perspective. The book addresses discoveries on hepatic progenitor cells, liver regeneration after chemical damage, and liver regeneration as a prime therapy for liver failure and disease.
By addressing the urgent need for translating basic research findings into clinically relevant modalities and potential therapeutic applications, the book provides the data needed to improve liver patient management.
Hundreds of full-color, graphic photographs and illustrations underline key elements and show researchers and students important aspects of liver transplantation, immunofluorescence, and other techniques used in liver regeneration.
- Summarizes current liver regeneration studies and discussions on expected discoveries
- Provides an overview of standard scientific and cutting-edge technologies to study liver regeneration
- Presents details on the molecular mechanisms that affect liver regeneration
- Highly illustrated, with hundreds of full-color, graphic photographs and illustrations to enhance the learning process
Zielgruppe
<p>Researchers in the area of liver biology </p>
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
Chapter 1. Introduction to Liver Regeneration: History and General Principles
Chapter 2. Models to Study Liver Regeneration
Chapter 3. Alternative Models to Study Liver Regeneration: Zebrafish
Chapter 4. The Priming and Progression Theory of Liver Regeneration
Chapter 5. Primary and Secondary Mitogen Theory of Liver Regeneration
Chapter 6. Developmental Pathways in Liver Regeneration
Chapter 7. Mechanisms of Termination of Liver Regeneration
Chapter 8. Modulation of Extracellular Matrix During Liver Regeneration
Chapter 9. Role of Chemokines
Chapter 10. Role of Nuclear Receptors
Chapter 11. Role of Developmental Morphogens in Liver Regeneration
Chapter 12. Regulation of Cell Cycle during Liver Regeneration
Chapter 13. Role of microRNAs and Long Non-Coding RNAs in Liver Regeneration
Chapter 14. Changes in Hepatocyte Ploidy during Liver Regeneration
Chapter 15. Role of Endothelial Cells in Liver Regeneration
Chapter 16. Use of Computational Biology, Omics Technologies to Understand Liver Regeneration
Chapter 17. Mitogen Induced Cell Proliferation in the Liver
Chapter 18. Effect of Nutritional Diversity on Liver Regeneration
Chapter 19. Introduction of Hepatic Progenitor Cells
Chapter 20. Cellular Transdifferentiation in the Liver
Chapter 21. Activation of Hepatic Progenitor Cells in Liver Regeneration After Chemical Injury to the Liver
Chapter 22. Hepatic Progenitor Cells and iPS Cells as a Source of Mature Hepatocytes
Chapter 23. Progenitor Cell Transplantation: Experimental Models
Chapter 24. Liver Regeneration as a Therapy for Acute Liver Failure
Chapter 25. Liver Regeneration Following Liver Transplantation
Chapter 26. Hepatocyte Transplantation Therapy
Chapter 27. Liver Regeneration: The Biliary Perspective
Contributors
Gianfranco Alpini Department of Internal Medicine, College of Medicine, Texas A&M University Health Science Center Division of Research, Central Texas Veterans Health Care System, and BaylorScott & White Digestive Disease Research Center, BaylorScott & White, Temple, Texas, USA Udayan Apte Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas, USA Vishakha Bhave Philadelphia College of Osteopathic Medicine, School of Pharmacy, Suwanee, Georgia, USA Alicia R. Brown Pediatric Stem Cell Research and Hepatic Disorders, Child Health Research Institute, Department of Pediatrics, University of Florida, Gainesville, Florida, USA Jean S. Campbell Northwest Liver Research Program, and Department of Pathology, University of Washington, Seattle, Washington, USA Daniel Cook Daniel Baugh Institute for Functional Genomics and Computational Biology, Department of Pathology, Anatomy and Cell Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, and Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA Anna Mae Diehl Division of Gastroenterology, Duke University, Durham, North Carolina, USA Lili Ding Department of Diabetes and Metabolic Diseases Research, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, USA, and Shanghai Key Laboratory of Complex Prescriptions and MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China Andrew W. Duncan Department of Pathology, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA Mingjie Fan Institute of Life Science, Taishan Medical University, Taian, China Christopher M. Freeman Department of Surgery, University of Cincinnati Medical Center, Cincinnati, Ohio, USA Shannon Glaser Department of Internal Medicine, College of Medicine, Texas A&M University Health Science Center Division of Research, Central Texas Veterans Health Care System BaylorScott & White Digestive Disease Research Center, BaylorScott & White, Temple, Texas, USA Wolfram Goessling Brigham and Women’s Hospital/Dana-Farber Cancer Institute, Harvard Medical School, Boston, and Harvard Stem Cell Institute and Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA Yuyan Han Department of Internal Medicine, College of Medicine, Texas A&M University Health Science Center, Temple, Texas, USA Jiansheng Huang Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA Wendong Huang Department of Diabetes and Metabolic Diseases Research, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, USA Alex B. Lentsch Department of Surgery, University of Cincinnati Medical Center, Cincinnati, Ohio, USA Yanfeng Li Department of Medicine, Division of Gastroenterology and Hepatology, and Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, New York, USA Pallavi B. Limaye Xenometrics LLC, Stilwell, Kansas, USA Joseph Locker Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA Mariana Verdelho Machado Division of Gastroenterology, Duke University, Durham, North Carolina, USA Luca Maroni Clinic of Gastroenterology, Università Politecnica delle Marche, “Ospedali Riuniti” University Hospital, Ancona, Italy Marco Marzioni Clinic of Gastroenterology, Università Politecnica delle Marche, “Ospedali Riuniti” University Hospital, Ancona, Italy Fanyin Meng Division of Research, Central Texas Veterans Health Care System, Temple, and BaylorScott & White Digestive Disease Research Center, BaylorScott & White, Texas, USA George K. Michalopoulos Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA Satdarshan Pal Singh Monga Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA Kari Nichole Nejak-Bowen Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA Yulia A. Nevzorova Department of Medicine III, University Hospital, Aachen, Germany Hiroyuki Nojima Department of Surgery, University of Cincinnati Medical Center, Cincinnati, Ohio, USA Bryon E. Petersen Pediatric Stem Cell Research and Hepatic Disorders, Child Health Research Institute, Department of Pediatrics, University of Florida, Gainesville, Florida, USA Liya Pi Pediatric Stem Cell Research and Hepatic Disorders, Child Health Research Institute, Department of Pediatrics, University of Florida, Gainesville, Florida, USA Zsuzsanna Polgar Department of Medicine, Division of Gastroenterology and Hepatology, and Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, New York, USA Michele T. Pritchard Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas, USA Debolina Ray Department of Internal Medicine, College of Medicine, Texas A&M University Health Science Center, Temple, Texas USA Kimberly J. Riehle Northwest Liver Research Program; Department of Surgery, and Department of Pathology, University of Washington, Seattle, Washington, USA Kevin Riggle Department of Surgery, University of Washington, Seattle, Washington, USA Paulette M. Robinson Pediatric Stem Cell Research and Hepatic Disorders, Child Health Research Institute, Department of Pediatrics, University of Florida, Gainesville, Florida, USA Jayanta Roy-Chowdhury Department of Medicine, Division of Gastroenterology and Hepatology Marion Bessin Liver Research Center, and Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, USA Namita Roy-Chowdhury Department of Medicine, Division of Gastroenterology and Hepatology; Marion Bessin Liver Research Center, and Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, USA David A. Rudnick Department of Pediatrics, and Department of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri, USA David A. Shafritz Marion Bessin Liver Research Center, Division of Gastroenterology and Liver Diseases, Albert Einstein College of Medicine, Bronx, NY, USA David C. Sullivan Pediatric Stem Cell Research and Hepatic Disorders, Child Health Research Institute, Department of Pediatrics, University of Florida, Gainesville, Florida, USA Christian Trautwein Department of Medicine III, University Hospital, Aachen, Germany Rajanikanth Vadigepalli Daniel Baugh Institute for Functional Genomics and Computational Biology, Department of Pathology, Anatomy and Cell Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia,...
