Basic Fundamentals of Drug Delivery

Erscheinungsjahr 2018
ISBN: 978-0-12-817909-3
Verlag: Elsevier Science

Buch, Englisch, 810 Seiten, Format (B × H): 187 mm x 241 mm, Gewicht: 1609 g

Basic Fundamentals of Drug Delivery covers the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable drug delivery system. The book also covers various approaches involved in optimizing the therapeutic performance of a biomolecule while designing its appropriate advanced formulation.

Autoren/Hrsg.

Weitere Mitwirkende

Tekade, Rakesh Kumar

Fachgebiete

• Wirtschaftswissenschaften Wirtschaftssektoren & Branchen Fertigungsindustrie Pharmaindustrie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Pharmazie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie

Inhaltsverzeichnis

1. Scientific rationale for designing controlled drug delivery systems 2. Current developments in excipient science: Implication of quantitative selection of each excipient in product development 3. Fundamentals of polymers science applied in Pharmaceutical Product Development 4. Use of polymers in controlled release of active agents 5. Co-polymers and block co-polymers in drug delivery and therapy 6. Pharmaceutical and biomedical applications of polymers 7. Levels of Drug targeting 8. Ligands for targeted drug delivery and applications 9. Transportation and bio interaction Properties in nanomaterials across biological systems 10. Importance of preliminary characterisation of nanoparticles in pharmaceutical product development 11. Biodegradable Block Copolymers and Their Applications For Drug Delivery 12. Bio-Nanotechnology in pharmaceutical research 13. Design and evaluation of ophthalmic delivery formulations 14. Design and fabrication of Brain targeted drug delivery 15. Cutaneous and transdermal drug delivery: Techniques and Delivery systems 16. Protein/peptide drug delivery systems: Practical considerations in Pharmaceutical Product Development 17. Nanocarriers in different preclinical and clinical stages 18. Clinical aspects and regulatory requirements for nanomedicines

Über Autor(innen)

Tekade, Rakesh Kumar
Dr Rakesh K Tekade, Assistant Professor of the Department of Pharmaceutics, investigates the design, development and characterization of targeted nanotechnology based formulations for the site specific delivery of therapeutic drugs, siRNA, microRNA, plasmids, proteins and peptide for the treatment of cancer. His current research encompasses development of novel polymeric nanomaterial for effective cytosolic delivery of anticancer bioactives. Dr Tekade's research is focused on designing a new generation of nanoparticles, which could identify the cancer cells and selectively deliver anticancer drugs and genes to inhibit the growth of cancer while sparing healthy tissues. His research work involves the applications of polymer chemistry, nanotechnology, molecular biology, pharmacokinetics/pharmacodynamics and imaging techniques. Dr Tekade has over 70 publications, 01 patent, 7 book chapters, and 3 editorial articles. He has delivered several invited research talks and presented research finding in more than 30 scientific conferences.