Buch, Englisch, 1094 Seiten, Book, Gewicht: 1940 g
Buch, Englisch, 1094 Seiten, Book, Gewicht: 1940 g
ISBN: 978-0-306-43665-9
Verlag: Springer US
The World Congress of In Vitro Fertilization and Alternate Assisted Reproduction, held in Jerusalem, Israel, 2-7 April, 1989, was the sixth in the sequence of these Congresses, but was the first to emphasize the major importance and the place of assisted reproductive technologies in the treatment of infertility. The eternal City of Jerusalem witnessed the gathering of more than 1500 participants from allover the world who shared and exchanged knowledge and up-to-date experience in this ever-evolving field. The high quality scientific contributions to the Congress culminated in the publication of this Proceedings. It embraces all-important aspects in the field of in vitro fertilization and alternate assisted reproduction. Papers on controversies and diversities of methods to stimulate the ovaries, imaging techniques, basic research and state-of-the-art papers on ovarian physiology, the role of GnRH and its analog, clinical aspects of IVF treatment and cryopreservation, up-to-date techniques in assisted reproductive technologies that are quickly developing in conjunction with IVF, were included. When should IVF be preferable to surgery? What are the ex pected up-to-date world results and what are the psychological, moral, ethical and religious implications? These are all the concerns of the treating team and are addressed here. Male factor infertility remains a frustrating problem, but advances in the understanding of sperm-egg interaction, sperm evaluation and preparation are reported. Micromanipulation emerges as a possible alternative to bring some relief to this problem, but it also promises to be central in promoting the field of prenatal genetic analysis.
Zielgruppe
Research
Autoren/Hrsg.
Weitere Infos & Material
1. Controversies in Induction of Ovulation.- Is There a Best Stimulation Protocol?.- Limitations in the Use of Combined Gonadotropin Releasing Hormone Analog and Human Menopausal Gonadotropin for In Vitro Fertilization.- The Combined Pituitary Suppression/Ovarian Stimulation Therapy: Myths and Realities.- Past, Present and Future of Gonadotropins.- 2. Aspects of Ovarian Stimulation in Medically Assisted Reproduction.- Physiology of Follicle Development in Stimulated Cycles.- Safe Gonadotropins.- IVF: LH Surge vs HCG.- Experience with GnRH-Agonists in Ovarian Stimulation.- The Association of Ovarian Hyperstimulation and Zygote Intrafallopian Transfer.- 3. Ovarian Physiology.- Control of Follicular Growth during the Primate Menstrual Cycle.- Growth Factor Modulation of Gonadotropin Action on Porcine Granulosa Cells.- Follicular Rupture during Ovulation: Activation of Collagenolysis.- Involvement of Calcium in the Transduction of the Hormonal Signal for Induction of Oocyte Maturation.- Hydration as the Key Event in Mucification of the Rat Cumulus.- Tumor Necrosis Factor (TNF?) and the Endogenous Prostaglandin Inhibitor (PGIn) in Bovine Follicles.- The Role of Tumor Necrosis Factor in Human Granulosa Cells and Early Embryo.- The Ovarian Renin-Angiotensin System and Compartmental Function in the Ovary.- The Physiology of Human Ovarian Prorenin-Angiotensin System.- 4. GnRH and GnRH Analogs: Basic Aspects.- Prolactin as a Possible Modulator of Gonadotropin Action on the Ovary.- Studies on Pharmacokinetics of LHRH Analogues after Different Modes of Administration.- Ovulation and Stress: Pathophysiology.- GnRH Peptides and Corpus Luteum Regulation.- GnRH Antagonists: New Developments for Indications in Reproductive Medicine.- 5. Alternate Assisted Reproduction.- IVF versus GIFT.- Patient Selection for Assisted Procreation.- Ultrasound-guided Catheterization of the Fallopian Tube for the Non-operative Transfer of Gametes and Embryos.- The Intratubal Transfer of Pronucleus and Early Embryonic Stage Embryos.- Tubal Embryo Transfer (TET) for the Treatment of Couples with Oligoasthenospermia.- The Present Perspectives of Direct Intraperitoneal Insemination.- Lessons Learned from IVC (Intra-vaginal Culture).- The Benefits of Tubal Transfer Procedures.- 6. IVF and Microsurgery in Cases if Mechanical Infertility.- Selection Criteria for Microsurgery, GIFT and IVF.- Tubo-tubal Anastomosis versus In Vitro Fertilization in the Management of Iatrogenic Infertility.- Ectopic Pregnancy and the Decision to Undergo IVF/ET.- 7. Clinical Aspects of IVF Treatments.- The Endocrinology of Stimulated Cycles and Influence on Outcome.- The Influence of Age, Uterine Length, Pre-post Egg Retrieval, Plasma Estradiol Drop, and the Number of Cleaved Embryos Transferred to the Uterus — on Outcome Following IVF/ET.- The Timing of Embryo Transfer and Implantation.- Oocyte Quality According to Protocols for Controlled Ovarian Hyperstimulation and Patients’ Age.- Luteal Phase and Embryonic Development in GnRH-Agonist/hMG-Cycles for In Vitro Fertilization.- Follicular Phase Gonadotropin-releasing Hormone Agonist and Human Gonadotropins: A Better Alternative for Ovulation Induction in In Vitro Fertilization.- Progesterone/Estradiol Ratios Predict Outcome in In Vitro Fertilization.- The Influence of Endometrial Preparation Protocols on Embryo Implantation in Human Cryopreservation Treatment.- The Replacement of Frozen-thawed Embryos: Natural or Artificial Cycles?.- Improvement of Ovarian Response to Induction of Superovulation with Combined Growth Hormone — Gonadotropin Treatment.- The Permissive Role of Growth Hormone in Ovulation Induction with Human Menopausal Gonadotropin.- Synchronization of Donor and Recipient Cycles in an Egg Donation Program: Fresh Versus Frozen/Thawed Embryo Transfers.- 8. Male Infertility.- Molecular Mechanisms of Mammalian Sperm-Zona Pellucida Interaction: Crosstalk Between Sperm and Egg.- Carbohydrated-mediated Sperm-Egg Interactions in Mammals.- The Function of Human Semen Coagulation and Liquefaction In Vivo.- The Role of IVF in Male Infertility.- IVF and Immunological Infertility.- Microsurgery, Andrology, and its Role in IVF.- New Possible Methods for Evaluation of Sperm Quality.- Ultramorphologic Characteristics of Human Sperm Cells.- Hemizona Assay: Assessment of Human Spermatozoa Dysfunction and its Correlation with In Vitro Fertilization Results.- 9. New Imaging Techniques and Reproduction.- to the Technology of Magnetic Resonance Imaging in Infertility.- Doppler Ultrasound in Infertility.- Transvaginal Color Doppler in the Study of Uterine Perfusion.- Blood Flow Measurements in the Uterine and Ovarian Arteries in Patients Undergoing IVF/ET and in Early Pregnancy, Performed with a Transvaginal Doppler Duplex System.- Ultrasonographic Prediction of Ovarian Hyperstimulation (OHS) after IVF.- Ten Years Experience with Simplifications in IVF.- 10. Gamete and Embryo Cryopreservation.- Comparison of Cryoprotectants and Stages of Human Embryo.- Ultrarapid Freezing.- World Results of Human Embryo Cryopreservation.- Influence of the Cooling Gradient and the Choice of Used Cryoprotectant on the Cryopreservation Outcome of Human and Animal Eggs.- Basic Concepts and Future Trends in Sperm Cryopreservation.- 11. Gamete, Embryo Donation and Surrogacy.- Oocyte Donation — State of the Art 1989.- Synchronization in Ovum Donation.- In Vitro Fertilization-Surrogate Gestational Pregnancy.- Success Rate of Surrogate Gestational Pregnancies Using In Vitro Fertilization Donor Oocytes.- Compassionate Family Surrogacy by IVF.- Semen Donation and Sex Selection.- 12. Implantation.- Recent Progress in Blastocyst Implantation Research.- Purified Human Cytotrophoblasts: Surrogates for the Blastocyst in In Vitro Models of Implantation?.- A Role for Platelet Activation Factor in Embryo Implantation.- Regulation of Trophoblast Invasion: The Requirement for Proteinase Cascade.- The Implantation Window in Humans after Fresh or Frozen-thawed Embryo Transfers.- 13. Laboratory Techniques.- Non-Invasive Biochemical Methods for Assessing Human Embryo Quality.- Pregnancy Rate and Pregnancy Outcome Associated with Laboratory Evaluation of Spermatozoa, Oocytes, and Pre-embryos.- Assessment of Embryo Quality and Viability through Embryo-iderived Platelet Activating Factor.- Coculture of Human Zygotes on Fetal Bovine Reproductive Tract Cells.- Gametes- and Embryo-Oviduct Interactions.- Epithelial Cells from Human Fallopian Tube in Culture.- 14. Enhancement of Fertilization by Micromanipulation.- Cytoplasmic Control of the Transformation of Sperm Nucleus into Male Pronucleus.- Partial Zona Dissection for Enhancement of Sperm Passage through the Zona Pellucida.- The Microinjection Technique and the Role of the Acrosome Reaction in Microfertilization.- Microinsemination of Human Oocytes.- Sperm Injection into the Perivitelline Space of the Oocyte.- Results of In Vitro Fertilization of Human Oocytes after Zona Drilling.- Rapid Sexing of Preimplantation Mouse Embryos by Blastomere Biopsy and Enzymatic Amplification.- 15. Genetic Analysis of the Pre-Embryo.- Proliferation of Cells Derived from the Biopsy of Pre-implantation Embryos.- Preimplantation Genetic Diagnosis: Approaches and Current Status.- The Feasibility of Preimplantation-Embryo Biopsy and Genetic Screening for Prenatal Diagnosis: Studies with Mice.- Genetics of Human Preimplantation Development: Implication in Embryo Viability Testing.- Nuclear Transfer.- MMTV/N-ras Transgenic Mice as a Model for Altered Capacitation Male Sterility and Tumorigenesis.- 16. Psychosocial Aspects of IVF and Alternate Assisted Reproduction.- Helping Patients End Treatment: The IVF Follow-mp Clinic as a Tool for Continuing Psychological Assessment.- Couples’ Experiences with In Vitro Fertilization: APhenomenological Approach.- Perceived Psycho-Social Features of IVF Compared to Other Treatments for Fertility.- Psycho-Social Profile of IVF Patients.- 17. World Collaborative Results and Outcome of IVF Pregnancies.- European IVF Results for 1987(a) — Attempts and Pregnancy Outcome.- IVF Results in Eastern Europe.- IVF Results in North America.- Pregnancy Rates and Perinatal Outcome in Australia and New Zealand.- Survey of Assisted Reproductive Technologies in Asia and Africa Up to 31st January 1988.- 18. Ethics, Religion and Legal Issues.- Ethical, Religious and Legal Debate on IVF and Alternate Assisted Reproduction.- 19. Editor’s Perspective.- Publish or Perish — An Editor’s Perspective.
