Bewley Protein-Carbohydrate Interactions in Infectious Diseases

1. Auflage 2007
ISBN: 978-1-84755-533-5
Verlag: Royal Society of Chemistry
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, Band Volume 5, 264 Seiten

Reihe: RSC Biomolecular Sciences

Protein-carbohydrate interactions is an exciting area of research with huge potential for development and exploration. These interactions are both widespread and diverse in biological processes and many play a crucial role in cellular recognition, attachment and adhesion. This is particularly true for host-pathogen interactions that lead to infectious diseases; as the surfaces of cells and pathogens display complex carbohydrate structures and carbohydrate binding proteins on their surface. Protein-Carbohydrate Interactions in Infectious Disease is part of the Biomolecular Science Series and provides a comprehensive overview of the subject, with contributions from leading experts in the field. Beginning with a general introduction, subsequent sections include: Atomic basis of protein-carbohydrate interactions, Structures and roles of Pseudomonas areuginosa lectins, Protein-carbohydrate interactions in enterobacterial infections, Retrocyclins: miniature lectins with potent antiviral activity, C-type lectin receptors that regulate pathogen recognition through the recognition of carbohydrates, Synthetic carbohydrate-based anti-malarial vaccines and glycobiology. With full colour throughout and an extensive bibliography this book is ideal for researchers interested in the area.

Autoren/Hrsg.

Bewley, Carole A

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Medizinische Mikrobiologie & Virologie
• Naturwissenschaften Biowissenschaften Kohlenhydrate
• Naturwissenschaften Biowissenschaften Proteinforschung

Inhaltsverzeichnis

Chemistry and Biology;

1: Atomic Basis of Protein-Carbohydrate Interactions. An Overview;

2: Mycobacterial Glycolipid and the Host: Role of Phenolic Glycolipids and Lipoarabinomannan;

3: Structures and Roles of Pseudomonas aeruginosa Lectins;

4: Protein-Carbohydrate Interactions in Enterobacterial Infections;

5: GM1 Glycomimetics and Bacterial Enterotoxins;

6: Retrocyclins: Miniature Lectins with Potent Antiviral Activity;

7: C-Type Lectin Receptors that Regulate Pathogen Recognition Through the Recognition of Carbohydrates;

8: Targeting Microbial Sialic Acid Metabolism for New Drug Development;

9: Synthetic Carbohydrate-Based Anti-Malarial Vaccines and Glycobiology;

10: Studies Towards a Rationally Designed Conjugate Vaccine for Cholera Using Synthetic Carbohydrate Antigens;

11: Carbohydrate Microarrays for High Throughput Analysis of Carbohydrate-Protein Interactions;