Total Synthesis of Bioactive Natural Products

Erscheinungsjahr 2019
ISBN: 978-0-08-102822-3
Verlag: Elsevier Health Sciences

Buch, Englisch, 350 Seiten, Format (B × H): 227 mm x 152 mm, Gewicht: 576 g

Total Synthesis of Bioactive Natural Products provides step-by-step guidelines for effectively synthesizing the most promising bioactive agents from a broad range of natural products. Beginning with a concise background that outlines the benefits and challenges faced in effective synthesis, the book goes on to provide individual outlines for approximately 100 of the most promising bioactive agents. Taking a logical, user-friendly approach, the systematic name, compound class, structure, natural source, pharmaceutical potential and synthetic routes for each structure are detailed, with clear illustrations throughout, making this book an essential and practical guide for anyone working with both synthesis and natural products.

Zielgruppe

<p>Natural products chemists, Synthetic chemists, Phytochemists, Medicinal chemists, Combinatorial chemists, Pharmaceutical Scientists, Plant Scientists, Manufacturers of natural products, Researchers in both academia and industry. </p>

Autoren/Hrsg.

Brahmachari, Goutam

Fachgebiete

• Naturwissenschaften Biowissenschaften Chemische Biologie, Synthetische Biologie
• Naturwissenschaften Chemie Organische Chemie

Inhaltsverzeichnis

Aeruginosins 298-A and B Ageladine A (+)-Ainsliadimer A-(+) (?)-Aiphanol (+)-Amphidinolide T1 Ancistroealaine A and Ancistrotanzanine B (?)-Andrographolide Anolignan A Anolignan B Antrocamphin A Arenamide A Atroviridin Bauhinoxepin J Beta-Lapachone Bombykol Bulbophylol-B Caminoside A (+)-Chaetocin Ciliatamides A and B Cylindol A Daedalin A 6-Deoxypladienolide D 7-Desmethoxyfusarentin and its methyl ether Etnangien (+)-Gliocladin B (+)-Harziphilone Hibarimicinone (±)-3-Hydroxy-beta-ionone Hyperforin Integric acid Jineol Karalicin (?)-Kunstleramide (±)-Limonin Linderaspirone A and Bi-linderone Lucidone (±)-Marinopyrrole A Martefragin A (?)-Melotenine A Microcin SF608 Nemorosone Nicotlactone A (?)-6-O-Desmethylantofine Oleocanthal (+)-3-Oxo-?-ionol Paecilomycin B Paecilomycine A? Pochonin A Rhinacanthin A Rubriflordilactone A (+)-Sattazolin Somocystinamide A (?)-Stagonolide A (±)-Steenkrotin A Thiaplakortone A and its semi-synthetic derivatives Vinigrol Withaferin A Withanolide A (+)-Xylarenal A Xyolide

Über Autor(innen)

Brahmachari, Goutam
Born on April 14, 1969 in Barala, a village in the district of Murshidabad (West Bengal, India), Goutam Brahmachari had his early education in his native place. He received his high school degree in scientific studies in 1986 at Barala R. D. Sen High School under the West Bengal Council of Higher Secondary Education (WBCHSE). Then, he moved to Visva-Bharati (a Central University founded by Rabindranath Tagore at Santiniketan, West Bengal, India) to study chemistry at the undergraduate level. After graduating from this university in 1990, he completed his master's in 1992, specializing in organic chemistry. After receiving his Ph.D. 1997 in chemistry from the same university, he joined his alma mater the next year and has been a full professor of chemistry since 2011. The research interests of Prof. Brahmachari's group include synthetic organic chemistry, green chemistry, natural products chemistry, and the medicinal chemistry of natural and natural product-inspired synthetic molecules. With more than 25 years of experience in teaching and research, he has produced over 260 scientific publications, including original research papers, review articles, books, and invited book chapters in the field of natural products and green chemistry. He has already authored/edited 27 books published by internationally reputed major publishing houses, namely, Elsevier Science (The Netherlands), Academic Press (Oxford), Wiley-VCH (Germany), Alpha Science International (Oxford), De Gruyter (Germany), World Scientific (Singapore), CRC Press (Taylor & Francis Group, USA), Royal Society of Chemistry (Cambridge), etc. Prof. Brahmachari serves several scientific bodies in India and abroad, and also many international journals as an editorial member. He has also been serving as co-editor-in-chief for Current Green Chemistry. Prof. Brahmachari is the founder series editor of the Elsevier Book Series 'Natural Product Drug Discovery'. Prof. Brahmachari is an elected fellow of the Royal Society of Chemistry and a recipient of the CRSI (Chemical Research Society of India) Bronze Medal-2021 (for his contribution to research in chemistry), Dr Basudev Banerjee Memorial Award-2021 (for his contribution to the field of chemical sciences) from the Indian Chemical Society, INSA (Indian National Science Academy) Teachers Award-2019, Dr Kalam Best Teaching Faculty Award-2017, and Academic Brilliance Award, 2015 (Excellence in Research). Prof. Brahmachari was featured in the World Ranking of the Top 2% Scientists (Organic Chemistry Category) in 2020-23, the AD Scientific World Ranking of Scientists in 2022-2024, and as the Scholar GPS Highly Ranked Scholar-2024 (Lifetime, securing a position in the top 0.05% of all scholars worldwide).