Multiple Action-Based Design Approaches to Antibacterials

1. Auflage 2021
ISBN: 978-981-16-0998-5
Verlag: Springer Nature Singapore

Buch, Englisch, 193 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 483 g

This book covers intentional design aspects for combinations of drugs, single-molecule hybrids with potential or actual multiple actions, pro-drugs which could yield multiple activity outcomes, and future possibilities. The approach of the book is interdisciplinary, and it provides greater understanding of the complex interplay of factors involved in the medicinal chemistry design and laboratory development of multiply active antibacterials. The scope of the book appeals to readers who are researching in the field of antibacterials using the approach of medicinal chemistry design and drug development. 

Zielgruppe

Research

Autoren/Hrsg.

Bremner, John

Fachgebiete

• Naturwissenschaften Chemie Physikalische Chemie Quantenchemie, Theoretische Chemie
• Naturwissenschaften Biowissenschaften Mikrobiologie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie
• Naturwissenschaften Chemie Organische Chemie Biochemie
• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)

Inhaltsverzeichnis

Introduction to Antibacterials.- Antibacterial Combinations.- Single Molecule Non-cleavable Multiply Active Antibacterials.- Design Principles and Development of Multiply Active Pro-drug Antibacterials.- Future Possibilities.

Über Autor(innen)

John Bremner was born in Perth, Western Australia and after completion of his undergraduate studies at the University of Western Australia he undertook a PhD at the Australian National University. After a further year at Harvard University as a Research Fellow he returned to Australia to take up a Lectureship in Chemistry at the University of Tasmania. Later, on sabbatical leave, he completed a Diploma in Chemical Pharmacology at the University of Edinburgh. In 1991 he was appointed as Professor of Organic Chemistry at the University of Wollongong in NSW, Australia. He retired in 2007 and is now an Emeritus Professor of the University of Wollongong. He is a Fellow of The Royal Australian Chemical Institute and received a Distinguished Fellow Award of the RACI in 2011. In 2001 he received the Adrien Albert Award in medicinal chemistry. He is also a Fellow of the Royal Society of Chemistry.