Strategies to Modify the Drug Release from Pharmaceutical Systems

2. Auflage 2025
ISBN: 978-0-443-33357-6
Verlag: Elsevier Science & Technology

Buch, Englisch, Format (B × H): 152 mm x 229 mm

Strategies to Modify the Drug Release from Pharmaceutical Systems, Second Edition is a concise reference on the current models used to meet the required therapeutic dosage and time of release. Updated with new strategies, mathematical models, routes of administration, and technologies, the book's content is presented in a concise and objective way. The six chapters cover general concepts, modification of drug release, classification of therapeutics systems for drug delivery - including a thorough discussion of passive versus active targeting. Chapter four describes the main mechanisms to control drug release - including a broad discussion on materials and technologies. Chapter five discusses mathematical and physicochemical models of drug release, including new mechanistic models and their fitting. Chapter six ends the book with a comprehensive, yet concise, review of drug delivery systems including 3D printing, nose-to-brain, environmentally responsive systems, and new lipid systems. Strategies to Modify the Drug Release from Pharmaceutical Systems, 2nd Edition is the perfect reference for pharmaceutical scientists and graduate students looking for a complete and objective reference on drug release. Materials scientists and chemists can also benefit from the up-to-date overview of mathematical models applied to drug release.

Autoren/Hrsg.

Bruschi, Marcos Luciano

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Pharmazie

Inhaltsverzeichnis

1. General concepts
2. Modification of drug release
3. Classification of therapeutic systems for drug delivery
4. Main mechanisms to control the drug release
5. Mathematical and physicochemical models of drug release
6. Drug delivery systems

Über Autor(innen)

Bruschi, Marcos Luciano
Marcos Luciano Bruschi, Ph.D., is Professor of Pharmaceutics and
Pharmaceutical Technology in the Department of Pharmacy at the State

University of Maringá (UEM), Paraná, Brazil. He gained a BSc in Pharmacy

(1996 - UEM, Brazil), a MD in Pharmaceutical Sciences (2002 - State University

of São Paulo - UNESP - Brazil) and a PhD in Pharmaceutical Sciences (2006 -

University of São Paulo - USP - Brazil and School of Pharmacy, Queen's

University of Belfast, Northern Ireland, UK). In 2013-2014, he is accomplishing

a Post-Doctoral Degree in Pharmaceutics in the School of Pharmacy, Queen's

University of Belfast (QUB - Northern Ireland, UK). He is registered with the

Brazilian Pharmaceutical Society and, in 1998, took up a lectureship in

Pharmaceutics in the School of Pharmacy, UEM, Brazil. In 1999, he was

appointed as a senior lectureship and to a personal Chair in Pharmaceutics and

Pharmaceutical Technology in 2006. His research concerns the development

and characterization of pharmaceutical dosage forms and drug delivery

systems, using natural or synthetic sources. Dr. Bruschi's work has involved the

development of novel drug delivery systems, with particular emphasis on

micro/nanoparticles, semisolids, bio/mucoadhesives, thermoresponsive systems,

liquid crystaline phases, and natural products. He is the author of three Brazilian

patent requests and over 150 research papers/communications.