Strategies to Modify the Drug Release from Pharmaceutical Systems

2. Auflage 2025
ISBN: 978-0-443-33357-6
Verlag: Elsevier Science

Buch, Englisch, 275 Seiten, Format (B × H): 191 mm x 235 mm

Strategies to Modify the Drug Release from Pharmaceutical Systems, Second Edition serves as a vital reference on contemporary models aimed at achieving the precise therapeutic dosage and timing of drug release. The book provides updated strategies, mathematical models, routes of administration, and technologies, all presented succinctly and objectively. This six-chapter guide covers general concepts of drug release modification and classification of therapeutic systems, including passive versus active targeting. It delves into mechanisms to control drug release, discussing materials and technologies, and introduces mathematical and physicochemical models of drug release.

Furthermore, it reviews drug delivery systems like 3D printing, nose-to-brain delivery, environmentally responsive systems, and new lipid systems, making it indispensable for pharmaceutical scientists, graduate students, materials scientists, and chemists.

Autoren/Hrsg.

Bruschi, Marcos Luciano

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Pharmazie

Inhaltsverzeichnis

1. General concepts
2. Modification of drug release
3. Classification of therapeutic systems for drug delivery
4. Main mechanisms to control the drug release
5. Mathematical and physicochemical models of drug release
6. Drug delivery systems

Über Autor(innen)

Bruschi, Marcos Luciano
Marcos Luciano Bruschi, Ph.D., is Professor of Pharmaceutics and
Pharmaceutical Technology in the Department of Pharmacy at the State

University of Maringá (UEM), Paraná, Brazil. He gained a BSc in Pharmacy

(1996 - UEM, Brazil), a MD in Pharmaceutical Sciences (2002 - State University

of São Paulo - UNESP - Brazil) and a PhD in Pharmaceutical Sciences (2006 -

University of São Paulo - USP - Brazil and School of Pharmacy, Queen's

University of Belfast, Northern Ireland, UK). In 2013-2014, he is accomplishing

a Post-Doctoral Degree in Pharmaceutics in the School of Pharmacy, Queen's

University of Belfast (QUB - Northern Ireland, UK). He is registered with the

Brazilian Pharmaceutical Society and, in 1998, took up a lectureship in

Pharmaceutics in the School of Pharmacy, UEM, Brazil. In 1999, he was

appointed as a senior lectureship and to a personal Chair in Pharmaceutics and

Pharmaceutical Technology in 2006. His research concerns the development

and characterization of pharmaceutical dosage forms and drug delivery

systems, using natural or synthetic sources. Dr. Bruschi's work has involved the

development of novel drug delivery systems, with particular emphasis on

micro/nanoparticles, semisolids, bio/mucoadhesives, thermoresponsive systems,

liquid crystaline phases, and natural products. He is the author of three Brazilian

patent requests and over 150 research papers/communications.