CRISPR-Cas-Based Genome Editing for Treating Human Diseases-Part A

Erscheinungsjahr 2024
ISBN: 978-0-443-31588-6
Verlag: Elsevier Science & Technology

Buch, Englisch, Format (B × H): 152 mm x 229 mm, Gewicht: 450 g

CRISPR-Cas-Based Genome Editing for Treating Human Diseases-Part A, Volume 208 represents CRISPR-Cas systems for genome editing. Currently, CRISPR-Cas systems are proven a key technology for targeted genome editing, which is acting as a simple, rapid, and cost-effective solution. CRISPR-Cas9 system is being used in microbial genome editing, mammalian genome editing, disease models, and more. It has shown potential in human disease treatment. However, it is not easy to find CRISPR-Cas systems genome editing in a single source.

This volume offers CRISPR-Cas systems for human diseases, bacterial disease, gut microbiome editing, viral disease, protozoan disease, fungal disease, stem cell therapy, CRISPR in epigenetics, CRISPR in cancer, autoimmune and blood disorders. In addition, it highlights a number of aspects of the CRISPR-Cas systems that can help the basic understanding of students, researchers, clinicians, entrepreneurs, and stakeholders to perform their research with great interest.

Autoren/Hrsg.

Weitere Mitwirkende

Singh, Vijay

Fachgebiete

• Naturwissenschaften Physik Angewandte Physik Biophysik
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Molekularbiologie

Inhaltsverzeichnis

1. Advances in CRISPR-Cas systems for human diseases
Vijai Singh
2. Advances in CRISPR -Cas systems for human bacterial disease
Indra Mani
3. Advances in CRISPR-Cas systems for gut microbiome
Indra Mani
4. Recent progress in CRISPR -Cas systems for human viral disease
Vijai Singh
5. Recent development in CRISPR -Cas systems for human protozoan diseases
ABHISHEKA BANSAL, Utkarsh Gangwar, Himashree Choudhury and Risha Shameem
6. Advances in CRISPR -Cas systems for fungal infections
Ajay Kumar I
7. Advances in CRISPR-Cas systems based cell and gene therapy
Aparna Jayachandran and Arpita Poddar
8. Advances in CRISPR-Cas systems for epigenetics
Mustafeez Mujtaba Babar, Mahnoor Ilyas, Alvina Gul and Jayakumar Rajadas
9. Current progress in CRISPR -Cas systems for cancer
Mustafeez Mujtaba Babar, Hajra Ali, Hunaiza Fatima, Alvina Gul and Jayakumar Rajadas
10. Current progress in CRISPR -Cas systems for autoimmune diseases
Ajay Kumar I
11. Advances in CRISPR -Cas systems for blood disorders
Deepak balaji Thimiri govindaraj and Mutsa Monica Takundwa

Über Autor(innen)

Singh, Vijay
Dr Vijai Singh serves as Professor and Dean (Research & Innovation) at School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. He was an Associate Professor in the Department of Biosciences, School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. Prior this this, he was an Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, India and also an Assistant Professor in the Department of Biotechnology at the Invertis University, Bareilly, India. Prior to that, he was a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He received his Ph.D. in Biotechnology from the National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India with a research focus on the development of molecular and immunoassays for diagnosis of Aeromonas hydrophila. His research interests are focused on building novel biosynthetic pathways for production of medically and industrially important biomolecules. Additionally, his laboratory is working on CRISPR-Cas9 tools for genome editing. He has more than 11 years of research and teaching experience in synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has published 100 articles, 70 book chapters, 17 books and 3 patents. He serves as an associate editor, editorial board member, and reviewer of several peer-reviewed journals. He is also a member of the Board of Study and Academic Council of Indrashil University and is the Member Secretary of the Institutional Biosafety Committee (IBSC) at the same University.