Investigative and Predictive DNA

Erscheinungsjahr 2025
ISBN: 978-0-443-30128-5
Verlag: Elsevier Science

Buch, Englisch, 600 Seiten, Format (B × H): 191 mm x 235 mm

Investigative and Predictive DNA Testing delves into the cutting-edge of DNA analysis, presenting a comprehensive guide that unlocks the potential of DNA in solving complex cases. This book stands as a vital resource for students, practitioners, and researchers in fields such as biology, zoology, medicine, anthropology, microbiology, and genetics. Designed for those with a basic understanding of biological sciences, it is particularly beneficial for graduate, post-graduate, and research level students. The book explores the evolution of DNA analysis, focusing on predictive methods and investigative leads such as ancestry, lineage, and phenotype.

Each chapter, contributed by internationally renowned experts, highlights the transformative role of artificial intelligence and machine learning in enhancing the accuracy and utility of DNA analysis. The book is comprised of various sections, starting with fundamental concepts of investigative and predictive DNA analysis, followed by technological advancements in the field, and concluding with the challenges and future concerns of DNA analysis. It serves as an indispensable tool for anyone looking to expand their knowledge and skills in DNA analysis, making it a must-read for the scientific community.

Autoren/Hrsg.

Dash, Hirak Ranjan

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)

Inhaltsverzeichnis

Module I: Conventional Forensic DNA Analysis
1. Fundamentals and Principles of Forensic DNA Analysis
2. Autosomal STR analysis and its usefulness in forensic DNA analysis
3. Detection and identification of forensically relevant body fluids
4. Use of lineage markers in conventional forensic DNA analysis
5. Analysis of mitochondrial DNA and its aid in forensic investigation
6. Effectiveness of conventional forensic DNA analysis in criminal investigation Module

II: Technological advancements in forensic DNA analysis
7. Advancements in Biotechnology for Trace evidence analysis
8. Understanding RAPID DNA and its application
9. Rapidly Mutating Y-STRs in Forensic DNA analysis
10. Use of biallelic genetic markers in forensic DNA analysis
11. Epigenetics and its application in forensic analysis
12. Microbial approaches to forensic investigation
13. Probabilistic Genotyping techniques and their applications
14. Application of genetics in Archaeological investigation
15. Digital PCR: a revolution in forensic DNA analysis
16. Role of Nanotechnology in forensic DNA analysis
17. Advancements in wildlife forensic DNA analysis Module

III: Predictive Forensic DNA analysis
18. Molecular Autopsy for analysis of Sudden Unexplained death cases
19. Artificial Intelligence and Machine Learning in Forensic DNA analysis
20. Prediction of lineage for generating investigative leads
21. Prediction of Externally Visible Characteristics and its in role in forensic investigation
22. Prediction of Ancestry and its role in forensic investigation
23. The advent of Investigative Genetic Genealogy
24. Contribution of advanced molecular techniques in investigation of Cold cases

Module IV: Challenges and Concerns in Forensic DNA analysis
25. Ethical issues in forensic DNA analysis
26. DNA profiling and databases: issues and challenges
27. Challenges in Interpretation of compromised cases by DNA profiling
28. Challenges of DNA Fingerprinting in Disaster Victim Investigations
29. Forensic Implications of PCR Inhibitors
30. Assessment of Reliability and Reproducibility of forensic DNA profiling results

Über Autor(innen)

Dash, Hirak Ranjan
Dr. Hirak Ranjan Dash is an Assistant Professor of Forensic Biotechnology at the National Forensic Sciences University, Delhi Campus, India. He obtained his PhD degree in Life Science from the National Institute of Technology, Rourkela, India. Previously, he served as a DNA expert at Forensic Science Laboratory, Madhya Pradesh, India. His research interests include forensic microbiology, microbial phylogeny, forensic DNA analysis, genetic markers, and next generation sequencing. He has published 50 research papers and 9 books. He has previously received a research fellowship from the Indian Academy of Science. He is a pioneer in India working on NGS-based forensic DNA analysis. He is a life member of the Association of Microbiologists of India, International Society of Forensic Geneticists, and Asian Federation of Biotechnologists.