A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities

2012
ISBN: 978-1-4614-2011-8
Verlag: Springer

Buch, Englisch, 507 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 809 g

Emotional, behavioral, and neuropsychiatric conditions are common in individuals with intellectual disabilities (IDs), most notably epilepsy, aggression, self-injurious behaviors, and bipolar and other mood disorders. Despite the prevalence of such problems, there is a scarcity in the literature of reliable information on medical treatments for those with IDs.
A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities provides a detailed framework for prescribing for this challenging population. Featuring the most up-to-date information on factors that inform prescribing, the Guide addresses basic issues and controversies (e.g., the rift between evidence-based and personalized medicine) in treating adults with cognitive deficits. Clients' specific needs are emphasized in developing appropriate and effective pharmacological intervention for improved outcomes and quality of life. Drugs discussed in the Guide include carbamazepine, clonazepam, diazepam, ethosuximide, felbamate, gabapentin, lacosamide, lamotrigine, levetiracetam, lithium, lorazepam, oxcarbazepine, phenobarbital, phenytoin, pregabalin, primidone, rufinamide,  tiagabine, topiramate, valproate, and zonisamide. For each of these compounds, the guidelines cover:

Indications for use; relative and absolute contraindications.Assessment during treatment; therapeutic drug monitoring; warning signs and symptoms for caretakers.Dosage: administration; initial and maximum recommended dosage; modifications associated with drug-drug interactions, personal characteristics, and (where appropriate) genetic variations.Adverse drug reactions: common, relatively uncommon, and potentially lethal, plus risk of metabolic syndrome.Guidelines for discontinuation.References, tables, and drug utilization reviews.A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities is an indispensable decision-making reference for psychiatrists, neuropsychologists, psychopharmacologists, neurologists, internists, and clinical psychologists.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

De Leon, Jose

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Psychiatrie, Sozialpsychiatrie, Suchttherapie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakotherapie, Psychopharmakotherapie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Neuropharmakologie, Psychopharmakologie

Inhaltsverzeichnis

1. Introduction.- 2. A Practitioner’s Guide to Prescribing Carbamazepine for Adults with Intellectual Disabilities.- 3. A Practitioner’s Guide to Prescribing Clonazepam for Adults with Intellectual Disabilities.- 4. A Practitioner’s Guide to Prescribing Diazepam for Adults with Intellectual Disabilities.- 5. A Practitioner’s Guide to Prescribing Ethosuximide for Adults with Intellectual Disabilities.- 6. A Practitioner’s Guide to Prescribing Felbamate for Adults with Intellectual Disabilities.- 7. A Practitioner’s Guide to Prescribing Gabapentin for Adults with Intellectual Disabilities.- 8. A Practitioner’s Guide to Prescribing Lacosamide for Adults with Intellectual Disabilities.- 9. A Practitioner’s Guide to Prescribing Lamotrigine For Adults with Intellectual Disabilities.- 10. A Practitioner’s Guide to Prescribing Levetiracetam for Adults with Intellectual Disabilities.- 11. A Practitioner’s Guide to Prescribing Lithium for Adults with Intellectual Disabilities.- 12. A Practitioner’s Guide to Prescribing Lorazepam for Adults with Intellectual Disabilities.- 13. A Practitioner’s Guide to Prescribing Oxacarbazepine for Adults with Intellectual Disabilities.- 14. A Practitioner’s Guide to Prescribing Phenobarbital for Adults with Intellectual Disabilities.- 15. A Practitioner’s Guide to Prescribing Phenytoin for Adults with Intellectual Disabilities.- 16. A Practitioner’s Guide to Prescribing Pregabalin for Adults with Intellectual Disabilities.- 17. A Practitioner’s Guide to Prescribing Primidone for Adults with Intellectual Disabilities.- 18. A Practitioner’s Guide to Prescribing Rufinamide for Adults with Intellectual Disabilities.- 19.  A Practitioner’s Guide to Prescribing Tiagabine for Adults with Intellectual Disabilities.- 20. A Practitioner’s Guide to Prescribing Topiramate for Adults with Intellectual Disabilities.- 21. A Practitioner’s Guide to Prescribing Valproate forAdults with Intellectual Disabilities.- 22. A Practitioner’s Guide to Prescribing Zonisamide for Adults with Intellectual Disabilities.- 23. A Practitioner’s Guide to Prescribing Non-oral Antiepileptics for Adults with Intellectual Disabilities.- 24. Conclusion.

Über Autor(innen)

Jose de Leon, M.D., is Professor in the Colleges of Medicine and Pharmacy, University of Kentucky, Lexington. He has directed the Mental Health Research Center at Eastern State Hospital for 14 years. He assists clinicians caring for patients with complex psychiatric illnesses at public facilities all over Kentucky by sharing his psychiatric and medical expertise with psychiatrists at state mental retardation (intellectual disability) and mental health  facilities. He investigates deaths and recommends specific interventions for improving care standards and is working on developing specialized pharmacological guidelines for mental retardation (intellectual disability) facilities. The pharmacological guidelines on antipsychotics have been published in the journal Research in Developmental Disabilities. An expert in psychopharmacology and pharmacogenetics, Dr. de Leon’s research career has been prolific. To date, he has published more than 200 peer-reviewed manuscripts in scientific journals included in PubMed. According to a computer search in the ISI Web of Science in April 2010, Dr. de Leon’s scientific publications have been cited in the literature more than 4,000 times. And Dr. de Leon’s “h” index is 35 (he has at least 35 articles with =35 citations).