Pharmacological Effects of Ethanol on the Nervous System

1. Auflage 1995
ISBN: 978-0-8493-8389-2
Verlag: CRC Press

Buch, Englisch, 480 Seiten, Format (B × H): 178 mm x 254 mm, Gewicht: 1048 g

Reihe: Handbooks in Pharmacology and Toxicology

This book dissects the effects of ethanol on the major neurotransmitter systems affected by ethanol and correlates these actions with the behavioral consequences. The subject is approached first from the perspective of the neurochemical system and the behaviors resulting from ethanol's effects on that system. The behaviors themselves are discussed in later chapters. Some older theories of the effects of ethanol such as the membrane fluidization hypothesis are evaluated in light of new and updated information. Fetal Alcohol Syndrome (FAS) as well as the structural damage in the brain by long term ethanol exposure are also discussed.

Autoren/Hrsg.

Deitrich, Richard A.

Erwin, V. Gene

Weitere Mitwirkende

Hollinger, Mannfred A.

Koob, George F.

Wood, W. Gibson

Dunwiddie, Thomas V.

Treistman, Steven N.

Wand, Gary S.

Collins, Allan C.

Breese, George R.

Henriksen, Steven J.

Browning, Michael D.

Tabakoff, Boris

Hoffman, Paula L.

Erwin, V. Gene

McCown, Thomas J.

Le, A.D.

Mayer, J. M.

Metten, Pamela

Crabbe, John C.

Alkana, Ronald L.

Davies, Daryl L.

Le, Anh Dzung

Nordmann, Roger

Rouach, Helene

Charness, Michael

Becker, Howard C.

Mulikin-Kilpatrick, Debra

Mihic, S. John

Eggeman, Kathryn T.

Lee, Francis Y.G.

Siggins, George R.

Samson, Herman

Draski, Laura J.

Chen, Wei-Jung A.

Hillborn, Matti

Harris, R. Adron

Maier, Susan Ellen

Nie, Zhiguo

Schweitzer, Paul P.

Madam, Samuel G.

West, James R.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft

Inhaltsverzeichnis

Introduction, R.A. Deitrich and V.G. ErwinOverview, G. KoobSection I: Effects of Ethanol at the Molecular/Cellular LevelCell Membrane Structure, W.G. Wood, F. Schroeder, R.M. Adibhatla, U. Igbavboa, N.A. AvdulovCalcium Channels, D. Mullikin-Kilpatrick and S.N. TreistmanChloride Channels/GABA, S.J. Mihic and R. A. HarrisGlutamate Receptors, B. Tabakoff and P.L. HoffmanCholinergic Systems, A.C. CollinsPhosphorylation, K. T. Eggeman and M.D. BrowningG-Proteins, F.Y.G. Lee, Sr. and G.S. WandAdenosine, T.V. DunwiddieNeurotensin, V.G. ErwinPeptides, G.R. Siggins, Z. Nie, P. Schweitzer, S. Madamba, S.J. HenriksenThyrotropin Releasing Hormone, T.J. McCown and G.R. BreeseSection II: Behavioral Effects of EthanolEthanol Intake, H.H. Samson and C.W. HodgeInitial Sensitivity, L.J. Draski and R.A. DeitrichAcute Tolerance, A.D. Le and J.M. MayerDependence and Withdrawal, P. Metten and J.C. CrabbeEthanol's Acute Effects on Thermoregulation: Mechanisms and Consequences, R. Alkana and A.D. LeSection III: Toxicity of Ethanol in the Central Nervous SystemFree Radicals, R. Nordmann and H. RouachFetal Damage-Mechanisms, W.-J.A. Chen, S.E. Maier, and J.R. WestStructural Damage, M.E. CharnessNeurological Damage and Stroke, M.E. HillbomFetal Damage-Behavior, H.C. Becker