Domb / Kumar Biodegradable Polymers in Clinical Use and Clinical Development

1. Auflage 2011
ISBN: 978-1-118-01580-3
Verlag: John Wiley & Sons
Format: EPUB
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 752 Seiten, E-Book

This book focuses on biodegradable polymers that are already inclinical use or under clinical development. Synthetic and naturalpolymers will be included. This excludes polymers that have beeninvestigated and did not reach clinical development.
The purpose of this book is to provide updated status of thepolymers that are clinical use and those that are now beingdeveloped for clinical use and hopefully will reach the clinicduring the next 5 years. The book provides information that ofinterest to academics and practicing researchers includingchemists, biologists and bioengineers and users: physicians,pharmacists.

Autoren/Hrsg.

Domb, Abraham J.

Kumar, Neeraj

Inhaltsverzeichnis

CONTRIBUTORS.
PREFACE.
PART I GENERAL.
1 Biodegradable Polymers in Drug Delivery (Jay Prakash Jain,Wubante Yenet, Abraham J. Domb, and Neeraj Kumar).
PART II BIODEGRADABLE POLYMERS OF NATURAL ORIGIN:PROTEIN-BASED POLYMERS.
2 Collagen (Wahid Khan, Deepak Yadav, Abraham J. Domb, andNeeraj Kumar).
3 Properties and Hemostatic Application of Gelatin (JalindarTotre, Diana Ickowicz, and Abraham J. Domb).
PART III BIODEGRADABLE POLYMERS OF NATURAL ORIGIN:POLYSACCHARIDES.
4 Chitosan and Its Derivatives in Clinical Use and Applications(Anuradha Subramanian, Kirthanashri Srinivasan Vasanthan, UmaMaheswari Krishnan, and Swaminathan Sethuraman).
5 Clinical Uses of Alginate (Udi Nussinovitch and AmosNussinovitch).
6 Dextran and Pentosan Sulfate -- Clinical Applications(Ramu Parthasarathi and Athipettah Jayakrishnan).
7 Arabinogalactan in Clinical Use (Rajendra P. Pawar,Babasaheb A. Kushekar, Bhaskar S. Jadhav, Kiran R. Kharat,Ravikumar M. Borade, and Abraham J. Domb).
PART IV BIODEGRADABLE POLYMERS OF NATURAL ORIGIN:POLYESTERS.
8 Polyhydroxyalkanoate (Kesaven Bhubalan, Wing-Hin Lee, andKumar Sudesh).
PART V SYNTHETIC BIODEGRADABLE POLYMERS.
9 Lactide and Glycolide Polymers (Kevin Letchford, AndersSodergard, David Plackett, Samuel Gilchrist, and HelenBurt).
10 Polyanhydrides Poly(CPP-SA), Fatty-Acid-Based Polyanhydrides(Ravikumar M. Borade, Abraham J. Domb, Archana A. Sawale,Rajendra P. Pawar, and Kiran R. Kharat).
11 Poly(e-Caprolactone-co-Glycolide): Biomedical Applications ofa Unique Elastomer (Kevin Cooper, Aruna Nathan, and MurtyVyakarnam).
12 Medicinal Applications of Cyanoacrylate (Rajendra P.Pawar, Ashok E. Jadhav, Sumangala B. Tathe, Bhimrao C. Khade, andAbraham J. Domb).
13 Polyethylene Glycol in Clinical Application and PEGylatedDrugs (Teerapol Srichana, and Tan Suwandecha).
PART VI INORGANIC POLYMERS.
14 Calcium-Phosphate-Based Ceramics for Biomedical Applications(Qing Lv, Kevin W.-H. Lo, Lakshmi S. Nair, and Cato T.Laurencin).
PART VII BIODEGRADABLE POLYMERS FOR EMERGING CLINICALUSES.
15 Biocompatible Polymers for Nucleic Acid Delivery (JeffSparks, and Khursheed Anwer).
16 Biodegradable Polymers for Emerging Clinical Use in TissueEngineering (Shalini Verma, Kalpna Garkhal, Anupama Mittal, andNeeraj Kumar).
17 Injectable Polymers (Shimon A. Unterman, Norman A. Marcus,and Jennifer H. Elisseeff).
PART VIII IPR ASPECTS OF BIODEGRADABLE POLYMERS.
18 Global Patent and Technological Status of BiodegradablePolymers in Drug Delivery and Tissue Engineering (ParikshitBansal, Shalini Verma, Wahid Khan, and Neeraj Kumar).
Index.

Über Autor(innen)

ABRAHAM J. DOMB is Professor of Medicinal Chemistry and NaturalProducts at the School of Pharmacy, the Hebrew University.Following time at Syntex Research in California, and MIT/Harvard asa research associate, he founded and headed the Drug Delivery andPolymer division at Nova Pharmaceuticals in Baltimore. Dr. Domb'sprimary research interests are in biopolymers, gene therapy,controlled drug delivery, cancer therapy, biodegradable polymers,hydrogels, coating of medical devices, nanoparticulate systems, andpolymeric complexes.
NEERAJ KUMAR is Assistant Professor of Pharmaceutics at theNational Institute of Pharmaceutical & Educational Research(NIPER), India. He obtained his PhD at the Indian Institute ofTechnology, Roorkee, India, before being appointed as Lady DavisPostdoctoral Fellow at the Hebrew University of Jerusalem. Dr.Kumar's current interests are in biomaterials, tissue engineering,drug delivery, and hydrogels.
AVIVA EZRA is a researcher at the Institute of Drug Research,School of Pharmacy, The Hebrew University of Jerusalem. She earnedher PhD in pharmaceutics from the School of Pharmacy. Dr. Ezra'sresearch interests include pharmaceutics, drug delivery systems,and pharmaceutical analysis.