Donnelly / Singh / Morrow Microneedle-mediated Transdermal and Intradermal Drug Delivery

1. Auflage 2012
ISBN: 978-1-119-95966-3
Verlag: John Wiley & Sons
Format: EPUB
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 280 Seiten, E-Book

Microneedles can be used for delivery of a wide range of drugsubstances for practically any medical condition and present a realopportunity for vaccines and medicines that are unsuitable for oraladministration or conventional patch delivery.
Microneedle-mediated Transdermal and Intradermal DrugDelivery covers the major aspects relating to the use ofmicroneedle arrays in enhancing drug delivery applications. Itprovides an overview of the various methods employed to design andproduce microneedles, from the different materials involved to theimportance of application methods. It carefully and criticallyreviews ongoing transdermal and intradermal delivery research usingmicroneedles and includes the outcomes of in vivo animal and humanstudies. Importantly, it also discusses the safety and patientacceptability studies carried out to date. Finally, the bookreviews the recent patents in microneedle research and describesthe ongoing developments within industry that will determine thefuture of microneedle-mediated transdermal and intradermal drugdelivery.
By an expert author team with practical experience in the designand development of drug delivery systems this is the only text thatprovides a comprehensive review of microneedle research intransdermal and intradermal drug delivery.

Autoren/Hrsg.

Donnelly, Ryan F.

Singh, Thakur Raghu Raj

Morrow, Desmond

Woolfson, A. David

Inhaltsverzeichnis

Preface.
About the Authors.
1 Transdermal Drug Delivery.
2 Microneedles: Design, Microfabrication and Optimization.
3 Microneedle Applicator Designs for Transdermal Drug Delivery Applications.
4 Transdermal Delivery Applications.
5 Microneedle-mediated Intradermal Delivery.
6 Clinical Application and Safety Studies of Microneedles.
7 Microneedles: Current Status and Future Perspectives.
Index.

Über Autor(innen)

Ryan F. Donnelly, Senior Lecturer in Pharmaceutics, Schoolof Pharmacy, Queen's University Belfast, UK
Thakur Raghu Raj Singh, Lecturer in Pharmaceutics, Schoolof Pharmacy, Queen's University Belfast, UK
Desmond I.J. Morrow, Honorary Research Fellow, School ofPharmacy, Queen's University Belfast, UK
A. David Woolfson, Chair in Pharmaceutics and Head of theSchool of Pharmacy, Queen's University Belfast, UK