Ekins Computer Applications in Pharmaceutical Research and Development

1. Auflage 2006
ISBN: 978-0-470-03722-5
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 806 Seiten, E-Book

Reihe: Wiley series in drug discovery and development

A unique, holistic approach covering all functions and phases ofpharmaceutical research and development
While there are a number of texts dedicated to individual aspectsof pharmaceutical research and development, this unique contributedwork takes a holistic and integrative approach to the use ofcomputers in all phases of drug discovery, development, andmarketing. It explains how applications are used at various stages,including bioinformatics, data mining, predicting human response todrugs, and high-throughput screening. By providing a comprehensiveview, the book offers readers a unique framework and systemsperspective from which they can devise strategies to thoroughlyexploit the use of computers in their organizations during allphases of the discovery and development process.
Chapters are organized into the following sections:
* Computers in pharmaceutical research and development: a generaloverview
* Understanding diseases: mining complex systems forknowledge
* Scientific information handling and enhancing productivity
* Computers in drug discovery
* Computers in preclinical development
* Computers in development decision making, economics, and marketanalysis
* Computers in clinical development
* Future applications and future development
Each chapter is written by one or more leading experts in the fieldand carefully edited to ensure a consistent structure and approachthroughout the book. Figures are used extensively to illustratecomplex concepts and multifaceted processes. References areprovided in each chapter to enable readers to continueinvestigating a particular topic in depth. Finally, tables ofsoftware resources are provided in many of the chapters.
This is essential reading for IT professionals and scientists inthe pharmaceutical industry as well as researchers involved ininformatics and ADMET, drug discovery, and technology development.The book's cross-functional, all-phases approach provides a uniqueopportunity for a holistic analysis and assessment of computerapplications in pharmaceutics.

Autoren/Hrsg.

Ekins, Sean

Weitere Mitwirkende

Wang, Binghe

Über Autor(innen)

SEAN EKINS, PHD, DSC, is an Adjunct Associate Professor in the Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy. Dr. Ekins is the author of more than seventy peer-reviewed papers and book chapters as well as several patents. He serves on editorial boards for the Journal of Pharmacological and Toxicological Methods, Drug Metabolism and Disposition, Drug Discovery Today, and Pharmaceutical Research.