Gene Therapy for Acute and Acquired Diseases

Softcover Nachdruck of the original 1. Auflage 2001
ISBN: 978-1-4613-5668-4
Verlag: Springer US

Buch, Englisch, 291 Seiten, Paperback, Format (B × H): 155 mm x 235 mm, Gewicht: 470 g

In recent years much enthusiasm and energy has been directed toward the development of human gene therapies, especially for inherited conditions and cancers. However, current gene transfer technology is limited in its transduction efficiency and ability to permanently and safely correct genomic defects. Thus the promise of gene therapy for these conditions is as yet unrealized. The progression of gene transfer technology will eventually surmount these limitations.
includes selected examples of ongoing studies in molecular genetics that have the potential to evolve into human therapies for acute illnesses. These chapters are intended to highlight lesser known applications of gene therapy for acquired disorders. It is expected that human gene therapy trials for these conditions will be forthcoming in the near future, leading to previously unimaginable therapies. Thus, this first-ever book about gene therapy for acute and acquired diseases is intended to serve as a glimpse into the future.

Zielgruppe

Research

Autoren/Hrsg.

Factor, Phillip H.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete AINS Intensivmedizin
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Chirurgie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin

Inhaltsverzeichnis

1 Rationale for the Use of Gene Therapy for Critical Illness.- 2 Gene Delivery in the ICU.- 3 Non-viral Based Gene Therapy for Pulmonary Disease.- 4 Gene Therapy for Acute Lung Injury.- 5 Gene Therapy for Preservation of Alveolar Endothelial and Epithelial Function.- 6 Gene Therapy for Fibroproliferative Phase ARDS.- 7 Gene Therapy for Asthma.- 8 Gene Therapy for Infectious Diseases.- 9 Gene Therapy for HIV and ABDS-Related Opportunistic Infections.- 10 Gene Therapy for Acute Kidney Diseases.- 11 Gene Therapy Strategies to Augment Contractile Function in Heart Failure.- 12 Gene Therapy for Cerebrovascular Disease and Central Nervous System Trauma.- 13 Gene Therapy for Applications for the Treatment of Acute Inflammatory Conditions.- 14 Facilitation of Organ Transplantation with Gene Therapy.- 15 Cardiac Angiogenesis and Gene Therapy: A Strategy for Myocardial Revascularization.