E-Book, Englisch, 121 Seiten
Reihe: Medical Intelligence Unit
Fanciulli Rb and Tumorigenesis
1. Auflage 2007
ISBN: 978-0-387-33915-3
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark
E-Book, Englisch, 121 Seiten
Reihe: Medical Intelligence Unit
ISBN: 978-0-387-33915-3
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark
Rb and Tumorigenesis examines how recent advances have demonstrated the interaction of Rb with chromatin remodeling enzymes. This new title explores the potential roles of these interactions in Rb functions and provides some evidence that distinct Rb co-repressor may target different genes in different phases of the cell cycle. This book will interest cell biologists, graduate students and researchers.
Autoren/Hrsg.
Weitere Infos & Material
1;CONTENTS;5
2;PREFACE;9
3;1 RB as a Positive Transcriptional Regulator during Epithelial Differentiation;10
4;2 pRb in the Differentiation of Normal and Neoplastic Cells;20
5;3 Regulation of DNA Replication by the Retinoblastoma Tumor Suppressor Protein;29
6;4 New Insights into Transcriptional Regulation by Rb: One Size No Longer Fits All;46
7;5 Regulation of Rb Function by Noncyclin Dependent Kinases;55
8;6 Diverse Regulatory Functions of the E2F Family of Transcription Factors;68
9;7 Regulation of E2F-Responsive Genes through Histone Modifications;82
10;8 Emerging Roles for the Retinoblastoma Gene Family;90
11;9 Rb and Cellular Differentiation;115
12;Index;127
