Electrochemical Detection in HPLC

Analysis of Drugs and Poisons
Erscheinungsjahr 2005
ISBN: 978-0-85404-532-7
Verlag: RSC Publishing

Buch, Englisch, 244 Seiten, Format (B × H): 155 mm x 234 mm, Gewicht: 517 g

Electrochemical Detection in HPLC: Analysis of Drugs and Poisons is the first monograph devoted to the application of this mode of analysis to the assay of exogenous compounds such as drugs in biological fluids and associated areas. The introductory chapters provide information on basic electrochemistry and HPLC-ED, and on trouble-shooting. The specialized area of thiol analysis is also discussed in detail. Salient practical details of published applications of the technique in analytical toxicology and related areas are provided in a standard format. Alternative techniques are suggested throughout. The emphasis is on the analysis of exogenous compounds, although catecholamines and other endogenous species are discussed in so far as they may be used as drugs. The practical nature of this book will make it useful to professionals working in the field. It will also be of benefit to analysts wishing to use HPLC-ED in the analysis of biological samples for analytes not specifically covered in the volume.

Zielgruppe

Academics, industrial chemists and technicians working in: chromatography, electrochemistry, and medicinal and pharmaceutical chemistry Chemistry/Food Science, general, Analytical Chemistry, Electrochemistry

Autoren/Hrsg.

Flanagan, Robert J

Perrett, David

Whelpton, Robin

Smith, Roger M

Weitere Mitwirkende

Smith, Roger M

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Pharmazeutische Technologie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Kosmetische Technologie
• Naturwissenschaften Chemie Analytische Chemie Instrumentelle Analytik, Chromatographie

Inhaltsverzeichnis

General Introduction: Basic Electrochemistry for the Separation Scientist: The Electrochemical Detector: Development and Trouble-shooting of HPLC-ED Methods: Thiols, Disulfides and Related Compounds:Applications of HPLC-ED in the Analysis of Drugs: Applications of HPLC-ED in Toxicology and Related Areas: Appendix. Non-aqueous Ionic Eluent Systems for Basic Drugs

Über Autor(innen)

R. J. Flanagan, Guy's & St Thomas' Hospital Trust, UK / D Perrett, Queen Mary's School of Medicine & Dentistry, London, UK / R Whelpton, Queen Mary, University of London, UK