Florence / Siepmann Modern Pharmaceutics

Basic Principles and Systems
5. Auflage 2013
ISBN: 978-1-4200-6565-7
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 656 Seiten

Reihe: Drugs and the Pharmaceutical Sciences

With over 100 illustrations, Volume 1 addresses the core disciplines of pharmaceutics (absorption, PK, excipients, tablet dosage forms, and packaging), and explores the challenges and paradigms of pharmaceutics.

Key topics in Volume 1 include:

• principles of drug absorption, chemical kinetics, and drug stability
• pharmacokinetics
• the effect of route of administration and distribution on drug action
• in vivo imaging of dose forms: gamma scintigraphy, PET imaging NMR, MRI, etc.
• powder technology
• excipient design and characterization
• preformulation
• optimization techniques in pharmaceutical formulation and processing
• disperse and surfactant systems
• the solid state, tablet dosage forms, coating processes, and hard and soft shell capsules
• parenteral products

Zielgruppe

Pharmaceutical, industrial, academic, and government scientists; pharmacy and pharmaceutical engineering students.

Autoren/Hrsg.

Florence, Alexander T.

Siepmann, Juergen

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Pharmazeutische Technologie

Inhaltsverzeichnis

Volume 1:

1. Pharmaceutics: New Challenges, New Paradigms
Alexander T. Florence and Juergen Siepmann

2. Principles of Drug Absorption
Michael Mayersohn

3. Pharmacokinetics
David W. A. Bourne

4. Factors Influencing Oral Drug Absorption and Drug Availability
Juergen Siepmann, Florence Siepmann, and Alexander T. Florence

5. Effect of Route of Administration and Distribution on Drug Action
Maureen D. Donovan

6. In Vivo Imaging of Dosage Forms
Zheng-Rong Lu

7. Chemical Kinetics and Drug Stability
David Attwood and Rolland I. Poust

8. The Solid State
Alastair J. Florence

9. Excipient Design and Characterization
Graham Buckton

10. Preformulation
Gavin W. Halbert

11. Disperse Systems
Wandee Rungseevijitprapa, Florence Siepmann, Juergen Siepmann, and Ornlaksana Paeratakul

12. Surfactants
David Attwood

13. Tablet Dosage Forms
Murat Turkoglu and Adel Sakr

14. Hard- and Soft-Shell Capsules
Larry L. Augsburger

15. Parenteral Products
James C. Boylan and Steven L. Nail

Index