Buch, Englisch, 782 Seiten, Format (B × H): 226 mm x 284 mm, Gewicht: 2359 g
Buch, Englisch, 782 Seiten, Format (B × H): 226 mm x 284 mm, Gewicht: 2359 g
Reihe: Handbook of Reagents for Organic Synthesis
ISBN: 978-1-119-95327-2
Verlag: Wiley
The Handbook is part of the Handbook of Reagents for Organic Chemistry series, aiming at collecting articles on a particular theme that individual researchers in academia or industry can use on a daily basis.
The Handbook starts with a section discussing the most important aspects of heteroarene functionalization. The introduction is followed by the alphabetical listing of the most relevant reagents drawn from the EROS database. The Editor, André Charette from the University of Montreal, has selected 120 reagent descriptions, many of them updated with heteroarene-specific reactions for this Handbook. Following the standard format for EROS, each article contains an overview of the synthesis and physical properties of the reagents or catalyst, conditions for its storage, and purification methods.
Given the importance of heteroarenes in biology and especially in medicinal chemistry, a Handbook that focuses exclusively on heteroarene functionalization has been long overdue. This Handbook will have a broad appeal to many individuals engaged in the area of medicinal chemistry, fine chemical synthesis and industrial-scale chemistry.
Key features:
- Builds on the success of the previously published Handbooks of Reagents for Organic Synthesis
- Compares the numerous new C-H functionalization reactions that have been developed in the past decade
- Heteroarene functionalization is widely used in the development of pharmaceuticals and other bioactive compounds
- Contains listings of secondary reagents for which more information is available in the online edition
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
Preface xi
Introduction xiii
Terminal Oxidants Finder xv
Oxidation Catalyst Finder xix
Recent Review Articles and Monographs xxv
Short Note on InChIs and InChIKeys xxvii
4-Acetamido-2,2,6,6-tetramethyl-1-piperidinyloxyl 1
4-Acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium Tetrafluoroborate 2
Bathocuproine 15
Bathophenanthroline 17
Benzenecarboperoxoic acid, 1, 1-dimethylethyl Ester 20
1,2-Benziodoxol-3(1H)-one, 1-Hydroxy, 1-Oxide, IBX 32
1,2-Benziodoxol-3(1H)-one, 1-Hydroxy, 1-Oxide, stabilized (stabilized IBX) 44 1,4-Benzoquinone 49
cis-4-Benzyloxy-a,a-bis-(3,5-dimethylphenyl)-Lprolinol (2S,4R)- 52
2,2_-Bipyrrolidines, (2S,2_S) and (2R,2_R) 54
2-[Bis-[3,5-bis(trifluoromethyl)Phenyl] [(trimethylsilyl)oxy]Methyl]Pyrrolidine 57
2,2-Bis[2-[4(S)-tert-butyl-1,3-oxazolinyl]]propane 59
Bis[[(1R,1__R)-3,3__-[(1R,2R)-1,2-cyclohexanediylbis [(nitrilo- N)methylidyne]]bis[2_-phenyl[1,1_-
binaphthalen]-2-olato- O]](2-)]di-µ-oxodi-titanium and Bis[[(1S,1__S)-3,3__-[(1S,2S)-1,2- cyclohexanediylbis[(nitrilo- N)methylidyne]]bis [2_-phenyl[1,1_-binaphthalen]-2-olato- O]](2-)]di- µ-oxodi-titanium 66
Bis(2,2-dimethylpropanoato - -O)phenyl-iodine 69
Bis(1-methyl-1-phenylethyl) Peroxide 77
1,2-Bis(phenylsulfinyl)ethane 79
N,N_-Bis(2,4,6-trimethylphenyl)imidazol-2-ylidene Palladium(I) Allyl Chloride 82
Bis(trimethylsilyl) Peroxide 87
Bromamine-T 91
N-tert-Butyl-N-chlorocyanamide 94
tert-Butyl Hydroperoxide 96
tert-Butyl Hypochlorite 126
tert-Butyl Peracetate 132
Calcium Hypochlorite 137
Chloramine-T 142
Chlorobenzene 150
Chloro[N,N_-ethylenebis(salicylideneaminato)] manganese 152
Chromium(VI) Oxide 157
Chromyl Acetate 163
Cobalt, [5,10,15,20-tetraphenyl-21H,23Hporphinato( 2-)- N 21, N 22, N 23, N 24]- 167
Cumyl Hydroperoxide 171
N,N_-(1R,2R)-1,2-Cyclohexanediylbis- [N-hydroxy-a-phenybenzeneacetamide] 179
1,5-Diaza-cis-decalin 183
N,N-
