G Protein-Coupled Receptors - Part B

Erscheinungsjahr 2023
ISBN: 978-0-323-99434-7
Verlag: William Andrew Publishing

Buch, Englisch, 300 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 450 g

G Protein-Coupled Receptors, Part B, Volume 195 represents the largest class of cell H103 surface proteins that have intricate involvement in nearly every physiological process in our body. Approximately one third of the clinically prescribed medicines target GPCRs and the quest to improve the exiting GPCR-targeting therapeutics continues. Sections in this volume include Adhesion G protein-coupled receptors: Structure and functions, Molecular and cellular mechanisms underlying brain region-specific cannabinoid receptor modulation by estradiol across the rodent estrus cycle, Probing the orphan receptors: Tools and directions, Asymmetric activation of Class C GPCRs, Common and selective signal transduction mechanisms of GPCRs, and much more.

Zielgruppe

<p>This book will appeal to any scientists interested in learning about the latest developments in the field of GPCR biology and drug discovery.</p>

Autoren/Hrsg.

Weitere Mitwirkende

Shukla, Arun K.

Fachgebiete

• Naturwissenschaften Biowissenschaften Molekularbiologie
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)

Inhaltsverzeichnis

Preface Arun K. Shukla 1. Adhesion G protein-coupled receptors: Structure and functions Doreen Thor and Ines Liebscher 2. Molecular and cellular mechanisms underlying brain region-specific cannabinoid receptor modulation by estradiol across the rodent estrus cycle Hye Ji J. Kim, Ayat Zagzoog, Tallan Black, Sarah L. Baccetto and Robert B. Laprairie 3. Probing the orphan receptors: Tools and directions Luca Franchini and Cesare Orlandi 4. Asymmetric activation of Class C GPCRs Hongnan Liu, Yanjun Li and Yang Gao 5. Common and selective signal transduction mechanisms of GPCRs Berkay Selçuk and Ogun Adebali 6. Appreciating the potential for GPCR crosstalk with ion channels Amy Davies and Alejandra Tomas 7. Recent advances in calcium-sensing receptor structures and signaling pathways Caroline M. Gorvin 8. Structural insights into promiscuous GPCR-G protein coupling Angela Carrión-Antolí, Jorge Mallor-Franco, Sandra Arroyo-Urea and Javier García-Nafría 9. Opioid signaling and design of analgesics Barnali Paul, Sashrik Sribhashyam and Susruta Majumdar

Über Autor(innen)

Shukla, Arun K.
Dr. Arun K. Shukla is a world leader in the field of GPCR biology and he is currently a Professor in the Department of Biological Sciences and Bioengineering at the Institute of Technology, Kanpur in India. Dr. Shukla's research program is focused on understanding the structure, function and regulation of G protein-coupled receptors with a long-term of designing novel therapeutics with minimized side-effects.