Emerging Paradigms for Antibiotic-Resistant Infections: Beyond the Pill

2024
ISBN: 978-981-97-5271-3
Verlag: Springer Nature Singapore

Buch, Englisch, 832 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 1441 g

This book delves into antibiotic resistance, offering insights into its emergence, mechanisms, and impact on global health. The book also scrutinizes over-prescription, agricultural use, and the scarcity of new drug development, while spotlighting the role of globalization in its propagation. It moves beyond conventional approaches, examining alternative strategies like phage therapy, immunotherapy, and nanotechnology. Highlighting precision diagnostics and the importance of policy implications, it navigates through public health strategies, surveillance, and international collaborations. Finally, it glimpses into the future, delineating the challenges, opportunities, and the urgency of action required to steer away from a post-antibiotic era. This book serves as an invaluable resource for students, researchers, and scientists in the fields of medicine, pharmacy, microbiology, and public health.

Zielgruppe

Research

Autoren/Hrsg.

Gangwar, Mayank

Nath, Gopal

Fachgebiete

• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie

Inhaltsverzeichnis

Part I. The Rise of Antibiotic Resistance.- Chapter 1. CRISPR-Cas Against Antimicrobial Resistant Pathogens.- Chapter 2. Upsurge in antibiotic resistant infections.- Chapter 3. Navigating the Challenges of Antibiotic Resistance: Origins, Mechanisms, and Global Responses.- Chapter 4. The Rise of Antibiotic Resistance “Silent Killer”.- Part II. Understanding Non-Antibiotic Advanced Therapies.- Chapter 5. Alternative approaches to counter multi-drug resistant bacterial pathogens.- Chapter 6. A potential strategy to manage antibiotic resistance is to employ anti-quorum sensing techniques.- Chapter 7. Revolutionizing Healthcare: Unleashing the Potential of Immunotherapies to Strengthen the Body’s Immune Defense Against Antibiotic-Resistant Pathogen.- Chapter 8. Beyond Antibiotics: Pioneering Strategies in Infection Control to Counter Antibiotic Resistance's Rising Tide.- Chapter 9. Revolutionizing Infection Control: Harnessing the Power of Stem Cells for Precision Antimicrobial Therapy.- Chapter 10. Combatting Antibiotic Resistance: Leveraging Fecal Microbial Transplantation for Gut Health.- Chapter 11. A Journey Beyond Resistance: Discovering The Promise of Non-Antibiotic Therapies.- Chapter 12. The Rise of Antibiotic Resistance: A Global Threat, Origin and Evolution of Antibiotic Resistance: Current Scenario and Future Prospective.- Chapter 13. Functional Nanomaterials in Antimicrobial Therapy for Antibiotic-Resistant Bacterial Infections.- Chapter 14. Association and contribution of dentistry in creating and sharing the burden of antibiotic-resistant microbial world.- Part III. Phage Therapy: Viral Warrior against Bacterial Invaders.- Chapter 15. Bacteriophages: The natural combatants to fight AMR.- Chapter 16. Reviving Phage Therapy: A Novel Approach to Treat Respiratory-associated Infections.- Chapter 17. The Art and Science of Defeating Superbugs: Present and Future of Phage Therapy.- Chapter 18. Phage therapy: Challenges in Its Development and Clinical Implementation.- Chapter 19. Breakthroughs in the Non-Antibiotic Therapies for Infectious Disease Treatment- From Phages to Peptides and Beyond.- Chapter 20. Synergistic effects of phage and antibiotic combinations against pathogenic bacteria.- Chapter 21. Phage Therapy Reimagined: Viral Solutions for Antibiotic Resistant Challenges.- Part IV. Immunotherapies: Boosting the Body's Defense.- Chapter 22. Diverse Properties of Tinospora Cordifolria (Giloy, Heart Leaved Moonseed) world wild use for Immunotherapies; Boosting the body defense and Immune support.- Part V.  Natural Antimicrobial Solutions: Nature's Weapon.- Chapter 23. Antimicrobial Efficacy of Rutin: Bridging the gap between Traditional Medicine and Modern Science.- Chapter 24. Beyond Pharmaceuticals: Tapping into Nature’s Weapons against Pathogenic Resilience.- Chapter 25. Exploring the potential of phytochemicals: A herbal boon against the MDR Bacteria associated with the chronic wounds.- Chapter 26. Harnessing Nature's Pharmacy: Medicinal Plants Combatting Bacterial Infections in the Aquatic Environment.- Chapter 27. Essential Oil- Natural Weapons to Overcome Antimicrobial Resistance.- Chapter 28. Antimicrobial activity of Plant and Cyanobacterial Secondary Metabolites for Therapeutic Advancements in Modern Medicine.- Chapter 29. Antimicrobial aspects of Brazilian Red Propolis and its compounds.- Chapter 30. Phytochemicals as source of novel antimicrobial agents against the rapidly evolving antimicrobial resistance.- Chapter 31. Natural antimicrobial compounds are an alternative to synthetic antibiotics.- Part VI. Bacteriophage-Derived Enzymes: Enlisting Nature's Allies.- Chapter 32. Phage Power: Harnessing Nature’s Arsenal in the Battle Against Microbial Threats for Sustainable Healthcare.- Chapter 33. Bacteriophages derived enzymes as potential alternatives for the treatment of MDR bacterial infections.- Chapter 34. Nature's Allies: Bacteriophage-Derived Enzymes to Combat Resistant Bacteria.- Chapter 35. Advancing Beyond Antibiotics: The Pioneering Use of Bacteriophage Enzymes.- Part VII. Overcoming Challenges and regulatory Hurdles.- Chapter 36. Overcoming Challenges and regulatory Hurdles for Sustainable Bacteriophage therapy products.- Chapter 37. Non-traditional Antibacterial Therapeutic: Focus on Safety, Manufacturing, and Regulatory Dynamics.- Part VIII. Future of Non-Antibiotics Therapies.- Chapter 38.Harnessing Artificial Intelligence and Machine Learning in the Battle Against Antimicrobial Resistant Infections.

Über Autor(innen)

Dr. Mayank Gangwar

Dr. Mayank is working at viral research and diagnostic laboratory, department of microbiology, institute of medical sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India. He is a Ph.D. in pharmacology with over 10+ years of research experience and holds an M.Pharm degree in the same field. His expertise encompasses drug metabolism, pharmacokinetics, microbiology, parasitology, virology, and drug-drug interactions. Driven by a passion for advancing scientific knowledge, he has established himself as a highly influential figure in pharmacological as well as virology research and has published various research papers. Known for his collaborative approach, he actively engages in conferences and workshops to foster interdisciplinary collaboration. Dr. Mayank's unwavering dedication to improving human health through his research continues to inspire researchers worldwide.

Dr. Gopal Nath

Dr. Gopal Nath is a distinguished microbiology professor at the department of microbiology, institute of medical sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India with expertise in bacteriophage therapy and gastrointestinal infection. He has various publications in his name. After completing his MBBS, MD, Ph.D. in microbiology, he focused on utilizing bacteriophages as therapeutic agents against antibiotic-resistant bacteria. Their postdoctoral research pioneered the application of bacteriophage therapy and opened new avenues for targeted antimicrobial treatments. As a professor, they mentored aspiring microbiologists and continued ground-breaking research. Dr. Gopal Nath publications cover diverse topics, including the isolation of novel bacteriophages and innovative therapeutic strategies. They are a sought-after speaker at international conferences, have served on editorial boards, and received prestigious awards for their significant contributions. Driven by their passion and expertise, they have become aleading figure in bacteriophage therapy, inspiring advancements in microbiology and offering hope in the battle against antibiotic resistance.