Buch, Englisch, Band 2546, 547 Seiten, Book w. online files / update, Format (B × H): 183 mm x 260 mm, Gewicht: 1252 g
Reihe: Methods in Molecular Biology
Methods and Protocols
Buch, Englisch, Band 2546, 547 Seiten, Book w. online files / update, Format (B × H): 183 mm x 260 mm, Gewicht: 1252 g
Reihe: Methods in Molecular Biology
ISBN: 978-1-0716-2564-4
Verlag: Springer US
This updated volume provides stepwise instructions for the analysis of numerous clinically important analytes by mass spectrometry. Mass spectrometry offers clinical laboratory scientists a number of advantages including increased sensitivity and specificity, multiple component analysis, and limited need for specialized reagents. These techniques are essential in laboratory fields including endocrinology, biochemical genetics, drug analysis, proteomics, and pathogen identification. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and practical, Clinical Applications of Mass Spectrometry in Biomolecular Analysis: Methods and Protocols, Second Edition is an ideal resource for clinical laboratory scientists who are already using or thinking of bringing mass spectrometry to their laboratories.
Zielgruppe
Professional/practitioner
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
1. Introduction to Mass Spectrometry for Bimolecular Analysis in a Clinical Laboratory
Y. Victoria Zhang and Uttam Garg
2. System Performance Monitoring in Clinical Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Shannon Haymond
3. Tandem Mass Spectrometry for the Analysis of Plasma/Serum Acylcarnitines for the Diagnosis of Certain Organic Acidurias and Fatty Acid Oxidation Disorders
David Scott, C. Clinton Frazee III, Bryce Heese, and Uttam Garg
4. Quantification of Plasma S-Adenosylmethionine and S-Adenosylhomocysteine Using Liquid Chromatography Electrospray Tandem Mass Spectrometry
Erland Arning, Brandi Wasek, and Teodoro Bottiglieri
5. Quantitation of Aldosterone in Serum or Plasma Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
J. Grace Van Der Gugten and Daniel T. Holmes
6. Comprehensive Determination of Amino Acids for Diagnosis of Inborn Errors of Metabolism
Stephen M. Roper, Annette L. Weindel, and Dennis J. Dietzen
7. Quantification of Branched-Chain Amino Acids in Plasma by High-Performance Liquid Chromatography-Tandem Mass Spectrometry (LC- MS/MS)
Hamed Piri-Moghadam, Alan Miller, Debra Pronger, Faye Vicente, Joel Charrow, Shannon Haymond, and David C. Lin
8. Quantitation of Butyrylcarnitine, Isobutyrylcarnitine, and Glutarylcarnitine in Urine Usin
