Proteoglycans in Lung Disease

1. Auflage 2002
ISBN: 978-0-8247-0815-3
Verlag: Taylor & Francis

Buch, Englisch, 480 Seiten, Format (B × H): 210 mm x 280 mm, Gewicht: 816 g

Reihe: Lung Biology in Health and Disease

Discusses new treatment strategies for malignant mesothelioma, pulmonary edema, fibrosis, asthma, emphysema, and bronchiectasis.

Proteoglycans in Lung Disease considers
- glycosaminoglycans as novel therapeutic agents or targets in lung disease

- the role of proteoglycans in determining mechanical behavior of lung tissue

- hyaluronan and its receptors in wound healing, inflammation, vasculogenesis, and angiogenesis

- the impact of small proteoglycans on matrix assembly

- versican as a modulator of cell adhesion, migration, and proliferation

- antiproliferative activity of heparin and its derivatives on pulmonary artery smooth muscle cells

- the effects of mechanical strain on proteoglycans

- the functions of proteoglycans in the vascular wall

- the effect of hypoxia on glycosaminoglycans in the lung

Comprised of more than 1940 references, Proteoglycans in Lung Disease

Zielgruppe

Professional Reference

Autoren/Hrsg.

Garg, Hari G.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Pneumologie, Atmung, Asthma

Inhaltsverzeichnis

Proteoglycans of the Lung

Peter J. Roughley
Hyaluronan in Lung Function: An Overview

Paul W. Noble
Morphological Tools for Studying Lung Proteoglycans

Paulo Sampaio Guitierrez and Vera Demarchi Aiello
Proteoglycans, Lung Physiology, and Mechanical Strain
Mara S. Ludwig
Hyaluronan and Its Receptors in Lung Health and Disease

Rashmin C. Savani and Horace M. Delisser
Hyaluronan and Hyaladherin Signaling in the Lung

Sara Hamilton, Eva A. Turley, and Fu-Sheng Wang
Hyaluronan in Malignant Mesothelioma
Anders L. Thylén and Gunnar Martensson
Matrix Proteoglycans in Development of Pulmonary Edema

Daniela Negrini, Alberto Passi, Giancarlo de Luca, and Giuseppe Miserocchi
The Role of Small Proteoglycans in the Formation of Fribrosis
Gunilla Westergren-Thorsson, Ellen Tufvesson, Erik Eklund, and Anders Malmstrom
Versican in the Cell Biology of Pulmonary Fibrosis
Clive R. Roberts
Decorin in Asthma

Anthony E. Redington
Role of Proteoglycans in the Development and Pathogenesis of Emphysema
Ymke M. Van Der Geld, Jeanette F. M. Van Straaten, Dirkje S. Postma, and Wim Timens
Proteoglycans in Normal and Pathological Bronchial Mucus
K. Ramakrishnan Bhaskar
Vascular Proteoglycans
Hannu Järveläinen and Thomas N. Wight
Degradation of Lung Matrix Proteoglycans in Bronchiectasis

Daisy Kwok Yan Shum and Mary Sau Man Ip
Effect of Hypoxia on Glycosaminoglycan Synthesis by Lung Cells
Eleni Papakonstantinou and George Karakiulakis and Michael Roth
Integrins, Proteoglycans, and Lung Disease
Jiahua Xu
Heparin as a Potential Therapeutic Agent to Reverse Vascular Remodeling

Hari G. Garg, Charles A. Hales, and Robert J. Linhardt

Author Index
Subject Index

Über Autor(innen)

Hari G. Garg