Concepts of Combating Chemoresistance in Cancer Therapeutics

Erscheinungsjahr 2025
ISBN: 978-0-443-33343-9
Verlag: Elsevier Science

Buch, Englisch, 440 Seiten, Format (B × H): 191 mm x 235 mm

Concepts of Combating Chemoresistance in Cancer Therapeutics explores the fundamental issues and challenges related to cancer chemotherapeutics, emphasizing mechanisms and factors that lead to chemoresistance in various cancer types. This book provides current updates on novel paradigms and mechanisms responsible for cancer chemoresistance, presenting comprehensive information in 15 chapters. In addition to introducing principles, mechanisms, and monitoring strategies for cancer drug resistance, the book highlights the role of nanotechnology in diagnostics and point-of-care solutions for early detection, screening, and control. It is an invaluable resource for health professionals, scientists, researchers, and students seeking knowledge in this field.

Autoren/Hrsg.

Goel, Honey

Srivastava, Saurabh

Singla, Richu

Talegaonkar, Sushama

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften

Inhaltsverzeichnis

1. Introduction to cancer drug resistance
2. Mechanisms of multi drug resistance in cancer
3. Therapeutic monitoring and adaptive strategies for combating drug resistance in cancer
4. Novel therapeutic interventions to overcome drug resistance in cancer: Targeting key regulators of the apoptotic pathway
5. Role of nutraceuticals in combating chemoresistance
6. Microfluidic devices for cancer detection and monitoring via liquid biopsy assay
7. Re-sensitization strategies towards autophagic resistance
8. Re-sensitization of cancer cells in non-solid tumors
9. Coupling of other modalities with chemotherapy to reverse chemoresistance
10. Nanotechnology for overcoming acquired drug resistance in GIT cancers
11. Nanotechnology for combating chemoresistance in peripheral cancers
12. Nanotechnology for combating chemoresistance in ovarian cancer
13. Nanotechnology for overcoming acquired drug resistance in CNS cancers
14. Advanced Strategies to improve the accumulation of nanotherapeutics in tumor
15. In silico-assisted prediction of chemoresistance

Über Autor(innen)

Singla, Richu
Dr. Richu carries more than 15 years of teaching and research experience and serving as Scientist-C, at Multidisciplinary Research Unit, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India funded by Directorate of Health and Research, Govt. of India. She fetched major project as women-Scientist-A from Department of Science and Technology, Govt. Of India. She is involved in multi-disciplinary research and various projects from different departments with faculty of Guru Gobind Singh Medical College and Hospital. Her thrust areas of his research include Probiotics, Molecular biology, RNA interference, targeted drug delivery, colon cancer biology and chemoprevention, and colon drug delivery systems. She has published more than 20 international peer reviewed publications with 500+ citations, published 10 book chapters and delivered talks/invited lectures at various national and international platforms. She has fetched international travel grants from DST and DBT. She has been also guiding many masters and PhD students

Goel, Honey
Dr. Honey has pursued his Masters from Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala and earned his Ph.D. from University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh. He carries more than 15 years of teaching and research experience and serving as Head, Department of Pharmaceutics at University Institute of Pharmaceutical Sciences and Research, Baba Farid University of Health Sciences, Faridkot (a reputed Autonomous State Health University Organization of Punjab, India). His thrust areas of his research include targeted drug delivery, colon cancer biology and chemoprevention, using natural polymers, Dosage form designing based on oral disintegrating technology and colon drug delivery systems. He has published more than 55 international peer reviewed publications with 600+ citations, edited 01 book, published 15 book chapters and delivered talks/invited lectures at various national and international platforms. He has been also guiding many masters and PhD students

Srivastava, Saurabh
Saurabh Srivastava is an Associate Professor of Pharmaceutics, at the National Institute of Pharmaceutical Education and Research, Hyderabad, India. His research interests include the development and optimization of industrially viable, feasible and scalable differentiated formulations, for the purpose of bioavailability enhancement, food effect minimization, repurposing/new indication, synergism for FDCs, and dose/dosing frequency reduction.