Neuronal Growth Cones

Erscheinungsjahr 2000
ISBN: 978-0-521-44491-0
Verlag: Cambridge University Press

Buch, Englisch, 288 Seiten, Format (B × H): 152 mm x 228 mm, Gewicht: 500 g

Reihe: Developmental and Cell Biology Series

'I had the good fortune to behold for the first time that fantastic ending of the growing axon. In my sections of the spinal cord of the three day chick embryo, this ending appeared as a concentration of protoplasm of conical form, endowed with amoeboid movements. It could be compared with a living battering ram, soft and flexible, which advances, pushing aside mechanically the obstacles which it finds in its path, until it reaches the region of its peripheral termination. This curious terminal club, I christened the growth cone.' (Santiago Ramón y Cajal, Recollections of My Life, 1937). In Neuronal Growth Cones, Phillip Gordon-Weeks presents the molecular biology of the behavior of growth cones. The book covers the basic morphology and behavior of growth cones, motility and neurite extension via the growth cone cytoskeleton, pathfinding, intracellular signalling, and synaptogenesis. It is the first detailed, critical analysis of all aspects of growth cone biology.

Autoren/Hrsg.

Gordon-Weeks, Phillip R.

Fachgebiete

• Naturwissenschaften Biowissenschaften Botanik Phytotomie, Pflanzenmorphologie
• Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Entwicklungsbiologie
• Naturwissenschaften Biowissenschaften Zellbiologie
• Naturwissenschaften Biowissenschaften Tierkunde / Zoologie Tiergenetik, Reproduktion
• Naturwissenschaften Biowissenschaften Botanik Pflanzenreproduktion, Verbreitung, Genetik
• Naturwissenschaften Biowissenschaften Biowissenschaften Evolutionsbiologie

Inhaltsverzeichnis

Foreword; Preface; 1. Introduction; 2. Motility and neurite extension: the growth cone cytoskeleton; 3. Pathfinding; 4. Intracellular signalling in growth cones; 5. Synaptogenesis; abbreviations; Index; References.