Govoni / Battaini Modification of Cell to Cell Signals During Normal and Pathological Aging

Erscheinungsjahr 2013
ISBN: 978-3-642-72729-0
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 9, 300 Seiten, eBook

Reihe: Nato ASI Subseries H:

The aging process involves changes in neurotransmission at different levels. The purpose of this book is to help define the state-of-the-art of the field and to give directives for future research on the aging brain. Following topics are presented: the comparison of normal and pathological aging at the anatomical and neurochemical level; the knowledge of the responses of the aging brain to drug treatment or environmental stress; the neuro/immune and neuro/endocrine setting during aging; and the definition of therapeutical approaches in normal aging. This book will interest physicians and pathologists as well as neurophysiologists.

Zielgruppe

Research

Autoren/Hrsg.

Govoni, Stefano

Battaini, Fiorenzo

Inhaltsverzeichnis

Functional Morphology and Cerebral Metabolism During Normal and Pathological Aging.- Functional morphology of neurons during normal and pathological ageing.- Functional morphology during normal and pathological ageing with emphasis on peptidergic transmission.- P.E.T. study of human brain metabolism in aging and dementia.- An experimental approach to the study of the functional derangement which follows aging of the brain and dementia.- Alzheimer’s disease causes metabolic uncoupling of associative brain regions beyond that seen in the healthy elderly.- Neurochemical, Neuroendocrine and Molecular Changes During Aging in Animals and in Man.- Neurotransmitters, genetics and aging.- Neuroendocrine aspects of aging.- The neuronotrophic hypothesis of the aging brain.- Example of age related changes of transducing mechanisms and of cerebral circuits.- Changes in calcium homeostasis during aging.- Dietary and neuroendocrine modulation of age related changes in dopaminergic action during aging.- Dopaminergic system in the aged brain: evidence for a selective loss of D-1 but not D-2 receptors.- Neurotransmitter changes in human brain during ageing.- The influence of age on neurotransmitters in the human brain.- Normal Versus Pathological Aging in Man:.- Senile dementias: an overview.- Growing points of the neurobiology of Alzheimer’s disease.- The Alzheimer tangle and aging.- New perspectives in Parkinson’s disease.- Guidelines of the care of the aged patients.- Subjective and objective health in aging: problems of assessment.- Drug development in geriatrics.