Gribble / Joule Progress in Heterocyclic Chemistry

1. Auflage 2009
ISBN: 978-0-08-091495-4
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 484 Seiten, Web PDF

This is the 20th annual volume of Progress in Heterocyclic Chemistry, which covers the literature published during 2007. As with previous volumes in the series, Volume 20 will enable the reader to keep abreast of developments in heterocyclic chemistry in an effortless way.
* A critical review of the heterocyclic literature published during 2007
* Presents specialized reviews
* Chapters all written by leading researchers in their field

Autoren/Hrsg.

Gribble, Gordon

Joule, J.

Inhaltsverzeichnis

1;Front Cover;1
2;Progress in Heterocyclic Chemistry;4
3;Copyright Page;5
4;Contents;6
5;Foreword;11
6;Editorial Advisory Board Members;12
7;Chapter 1. 2-Indolylacyl radicals in the synthesis of indole compounds;14
7.1;1.1 Introduction;14
7.2;1.2 Radical reactions in synthesis: a short overview;14
7.3;1.3 2-Indolylacyl radicals: intermolecular and cascade reactions;15
7.4;1.4 Intramolecular reactions of 2-indolylacyl radicals with alkenes;17
7.5;1.5 Intramolecular reactions of 2-indolylacyl radicals with aromatic and heteroaromatic systems;24
7.6;1.6 Conclusion;29
7.7;1.7 Acknowledgments;29
7.8;1.8 References;29
8;Chapter 2. Cascade reactions of carbonyl ylides for heterocyclic synthesis;33
8.1;2.1 Introduction;33
8.2;2.2 Carbonyl ylide cycloadditions;34
8.3;2.3 Conclusion;57
8.4;2.4 Acknowledgments;57
8.5;2.5 References;57
9;Chapter 3. Three-membered ring systems;60
9.1;3.1 Introduction;60
9.2;3.2 Epoxides;60
9.3;3.3 Aziridines;73
9.4;3.4 References;83
10;Chapter 4. Four-membered ring systems;87
10.1;4.1 Introduction;87
10.2;4.2 Azetidines, 3-azetidinones, and diazetines;87
10.3;4.3 Monocyclic 2-azetidinones (ß-lactams);90
10.4;4.4 Fused and spirocyclic ß-lactams;94
10.5;4.5 Oxetanes, dioxetanes, oxetanediones and 2-oxetanones (ß-lactones);95
10.6;4.6 Thietanes, ß-sultams, and related systems;98
10.7;4.7 Silicon and phosphorus heterocycles. miscellaneous;99
10.8;4.8 References;101
11;Chapter 5. Five-membered ring systems;107
11.1;Part 1. Thiophenes and Se/Te analogs;107
11.1.1;5.1.1 Introduction;107
11.1.2;5.1.2 Thiophene ring synthesis;107
11.1.3;5.1.3 Reactions of thiophenes;111
11.1.4;5.1.4 Non-polymeric thiophene organic materials;117
11.1.5;5.1.5 Thiophene oligomers and polymers;119
11.1.6;5.1.6 Thiophene derivatives in medicinal chemistry;124
11.1.7;5.1.7 Selenophenes and tellurophenes;126
11.1.8;5.1.8 References;128
11.2;Part 2. Pyrroles and benzo analogs;135
11.2.1;5.2.1 Introduction;135
11.2.2;5.2.2 Synthesis of pyrroles;135
11.2.3;5.2.3 Reactions of pyrroles;141
11.2.4;5.2.4 Pyrrole natural products and materials;145
11.2.5;5.2.5 Synthesis of indoles;146
11.2.6;5.2.6 Reactions of indoles;151
11.2.7;5.2.7 Carbazoles and azaindoles;154
11.2.8;5.2.8 Indole natural products;154
11.2.9;5.2.9 Biochemical and medicinal chemistry;158
11.2.10;5.2.10 References;158
11.3;Part 3. Furans and benzofurans;165
11.3.1;5.3.1 Introduction;165
11.3.2;5.3.2 Reactions;166
11.3.3;5.3.3 Synthesis;172
11.3.4;5.3.4 References;194
11.4;Part 4. With more than one N atom;203
11.4.1;5.4.1 Introduction;203
11.4.2;5.4.2 Pyrazoles and ring-fused derivatives;203
11.4.3;5.4.3 Imidazoles and ring-fused derivatives;209
11.4.4;5.4.4 1,2,3-Triazoles and ring-fused derivatives;216
11.4.5;5.4.5 1,2,4-Triazoles and ring-fused derivatives;221
11.4.6;5.4.6 Tetrazoles and ring-fused derivatives;223
11.4.7;5.4.7 References;226
11.5;Part 5. With N and S (Se) atoms;233
11.5.1;5.5.1 Introduction;233
11.5.2;5.5.2 Thiazoles;233
11.5.3;5.5.3 Isothiazoles;252
11.5.4;5.5.4 Thiadiazoles and selenodiazoles;258
11.5.5;5.5.5 1,3-Selenazoles, 1,3-selenadolidines and 1,3-tellurazoles;261
11.5.6;5.5.6 References;262
11.6;Part 6. With O and S (Se, Te) atoms;266
11.6.1;5.6.1 1,3-Dioxoles and dioxolanes;266
11.6.2;5.6.2 1,3-Dithioles and dithiolanes;268
11.6.3;5.6.3 1,3-Oxathioles and oxathiolanes;272
11.6.4;5.6.4 1,2-Dioxolanes;273
11.6.5;5.6.5 1,2-Dithioles and dithiolanes;273
11.6.6;5.6.6 1,2-Oxathioles and oxathiolanes;274
11.6.7;5.6.7 Three heteroatoms;274
11.6.8;5.6.8 References;274
11.7;Part 7. With O and N atoms;278
11.7.1;5.7.1 Isoxazoles;278
11.7.2;5.7.2 Isoxazolines;281
11.7.3;5.7.3 Isoxazolidines;284
11.7.4;5.7.4 Oxazoles;287
11.7.5;5.7.5 Oxazolines;291
11.7.6;5.7.6 Oxazolidines;296
11.7.7;5.7.7 Oxadiazoles;297
11.7.8;5.7.8 References;298
12;Chapter 6. Six-membered ring systems;302
12.1;Part 1. Pyridines and benzo derivatives;302
12.1.1;6.1.1 Introduction;302
12.1.2;6.1.2 Pyridines;302
12.1.3;6.1.3 Quinolines;315
12.1.4;6.1.4 Isoquinolines;321
12.1.5;6.1.5 Piperidines;324
12.1.6;6.1.6 References;334
12.2;Part 2. Diazines and benzo derivatives;346
12.2.1;6.2.1 Introduction;346
12.2.2;6.2.2 Reviews and general studies;346
12.2.3;6.2.3 Pyridazines and benzo derivatives;347
12.2.4;6.2.4 Pyrimidines and benzo derivatives;350
12.2.5;6.2.5 Pyrazines and benzo derivatives;363
12.2.6;6.2.6 References;368
13;Part 3. Triazines, tetrazines and fused ring polyaza systems;377
14;Part 4. With O and/or S atoms (2006);378
14.1;6.4.1 Introduction;378
14.2;6.4.2 Heterocycles containing one oxygen atom;379
14.3;6.4.3 Heterocycles containing one sulfur atom;398
14.4;6.4.4 Heterocycles containing two or more oxygen atoms;401
14.5;6.4.5 Heterocycles containing two or more sulfur atoms;403
14.6;6.4.6 Heterocycles containing both oxygen and sulfur in the same ring;405
14.7;6.4.7 References;406
15;Part 4. With O and/or S atoms (2007);412
15.1;6.4.1 Introduction;412
15.2;6.4.2 Heterocycles containing one oxygen atom;414
15.3;6.4.3 Heterocycles containing one sulfur atom;434
15.4;6.4.4 Heterocycles containing two or more oxygen atoms;436
15.5;6.4.5 Heterocycles containing two or more sulfur atoms;437
15.6;6.4.6 Heterocycles containing both oxygen and sulfur in the same ring;438
15.7;6.4.7 References;439
16;Chapter 7. Seven-membered rings;445
16.1;7.1 Introduction;445
16.2;7.2 Seven-membered systems containing one heteroatom;445
16.3;7.3 Seven-membered systems containing two heteroatoms;452
16.4;7.4 Seven-membered systems containing three or more heteroatoms;461
16.5;7.5 Seven-membered systems of pharmacological significance;463
16.6;7.6 Future directions;466
16.7;7.7 References;466
17;Chapter 8. Eight-membered and larger rings;472
17.1;8.1 Introduction;472
17.2;8.2 Carbon-oxygen rings;473
17.3;8.3 Carbon-nitrogen rings;475
17.4;8.4 Carbon-sulfur rings;477
17.5;8.5 Carbon-oxygen/carbon-nitrogen rings;478
17.6;8.6 Carbon-nitrogen-oxygen rings;479
17.7;8.7 Carbon-nitrogen-sulfur rings;481
17.8;8.8 Carbon-sulfur-oxygen rings;482
17.9;8.9 Carbon-nitrogen-sulfur-oxygen rings;483
17.10;8.10 Carbon-nitrogen-metal rings;483
17.11;8.11 Carbon-nitrogen-sulfur-metal rings;483
17.12;8.12 Carbon-phosphous-oxygen-metal rings;484
17.13;8.13 Carbon-nitrogen-phosphorus-sulfur-metal rings;485
17.14;8.14 References;485
18;Index;489