Guder Pre-Examination Procedures in Laboratory Diagnostics

Preanalytical Aspects and their Impact on the Quality of Medical Laboratory Results
1. Auflage 2015
ISBN: 978-3-11-033404-3
Verlag: De Gruyter
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 424 Seiten

Die Aussagekraft eines Laborbefundes hängt entscheidend von der Präanalytik ab, also von Prozessen, die vor der eigentlichen Messung der Proben im Labor ablaufen. Dieses Buch beschreibt alle präanalytischen Variablen - Indikation der Anforderung über Probengewinnung, Transport und Lagerung der Proben und Vorverarbeitung dieser für die Analyse - und definiert Qualitätskriterien der einzelnen Aspekte im Sinne einer evidenz-basierten Medizin.

Zielgruppe

Clinicians, nurses and laboratory professionals (phlebotomists, t

Autoren/Hrsg.

Guder, Walter G.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Labormedizin
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Medizinische Diagnose und Diagnostik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Kardiologie, Angiologie, Phlebologie

Inhaltsverzeichnis

Preface List of Contributing authors

1. General Part 1.1. Introduction and History of the Preanalytical Phase

Guder W.G. 1.2. From Diagnostic Strategies to Guidelines and Pathways. Benefits and Limitations of Laboratory Diagnostic Pathways.

Hoffmann G, Aufenanger J, Födinger M, Cadamuro J, von Eckardstein A, Hofmann W. 1.3. Definition of Influence and Interference Factors in the Preanalytical Phase. Guder W.G. 1.4. Extraanalytical Procedures and their Management in Total Turnaround Time Guder W.G.,Wisser H.

2. Types of Samples and Anatomic Site of Origin 2.1. What site of Sampling, Arterial, Venous or Capillary Blood ?

Guder W.G., Hagemann P 2.2. Special Preexamination Conditions in Newborns and Pediatric Patients.
Vassault A, Couderc R 2.3. Venous Blood Sampling (Phlebotomy)

Guder WG, Cornes M. 2.4. Arterial Sampling of Blood

Guder W.G., Hagemann P. 2.5. Capillary Sampling of Blood

Cornes M, Guder W.G. 2.6. Plasma or Serum? Which Anticoagulant to Use?
Guder W.G., Narayanan S. 2.7. Spot or Timed Urine, When and Why?

Guder W.G., Delange J 2.8. When are other Body Fluids to be Analyzed

Guder W.G. 2.9. Who is doing Phlebotomy in Europe?
Simundic A.M.

3. Biological Variables Influencing Laboratory Results 3.1 Age and Gender Differences; unavoidable Influences on Laboratory Results

Guder W.G. ,Narayanan S.

3.2 Variables during Sampling

Guder W.G., Narayanan S. 3.3 Food, Drinks and Smoking

Narayanan S, Guder W.G.

3.4 Effects of Herbs

Narayanan S., Young D.S

4. Source and Nature of Interferences of Analytical Procedures. 4.1 The Hemolytic Sample

Guder W.G., daFonseca-Wollheim F, Schmitt Y.M., Töpfer G.

4.2 The Lipemic Sample

Guder W.G., Nikolac N,Schmitt Y.M., Töpfer G.

4.3 The Icteric Sample

Guder W.G., da Fonseca-Wollheim F., Schmitt Y.M., Töpfer G.

4.4 Drug Interferences.
Sonntag O. 4.5 Interferences from Blood Sampling Device Materials on Clinical Assays. Part 1

Bowen R.A.R. Adcock - Funk D.

4.6 Interferences from Blood Sampling Device Materials on Clinical Assays, Part 2

Bowen R.A.R., Adcock - Funk D.
5. Sampling Techniques and Professions 5.1 Materials and Techniques of Sampling Blood and other Body Fluids, Contributions of Greiner- Bio-One.
Ivanov H, Präuer J, Schimpl M, Castelo-Rose G, Wiesner C, Ehrenfellner T. 5.2 Materials and Techniques of Sampling Blood from Sarstedt.

C. Seipelt 5.3 BD Preanalytical Systems - Diagnostic Sample Collection

Schlueter K., Church S.
6. Specimen Processing in the Preanalytical Phase

6.1 Sample Transport, Treatment after Arrival, Storage and Disposal

Guder W.G., Narayanan S. 6.2 Preanalytical Workflow Techniques and Procedures
Streichert T., von Meyer A.

7. Preanalytical Variables and Rules in Specific Fields of Medical Laboratory Diagnostics 7.1 Haemostaseology

Dempfle C-E., Toepfer G. 7.2 Haematology including Flow Cytometry of Blood Cells

Narayanan S.,Guder W.G. 7.3 Blood Gases, Ions and Electrolytes

Simundic A-M. 7.4 Clinical Chemistry: Metabolites, Enzymes, Hormones and Proteins

Narayanan S., Guder W.G.

7.5 Preanalytical Variables in Therapeutic Drug Monitoring

Narayanan S, Agrawal Y. 7.6 Preanalytical Variables in Microbiology

Narayanan S, Schuetz N. 7.7 Biobanking

Leichtle A., Findeisen P.

8. Quality Assurance and Auditing of the Preanalytical Phase 8.1 Auditing of the Preanalytical Phase

Petersmann A., Schlüter K., Nauck M. 8.2 Internal Quality assurance for Preanalytical Phase

Cadamuro J. 8.3 External Quality Assurance for the Preanalytical Phase

Kristensen G.B.B., Aakre K.M., Kristoffersen A.H., Sandberg S.

9. Annex: Samples and Stability of Analytes Index

Über Autor(innen)

Walter Guder, München, Germany; Sheshadri Narayanan, Cornell University, New York, USA.