Gvozdjáková | Mitochondrial Medicine | Buch | 978-1-4020-6713-6 | sack.de

Buch, Englisch, 409 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 846 g

Gvozdjáková

Mitochondrial Medicine

Mitochondrial Metabolism, Diseases, Diagnosis and Therapy
2008
ISBN: 978-1-4020-6713-6
Verlag: Springer Netherlands

Mitochondrial Metabolism, Diseases, Diagnosis and Therapy

Buch, Englisch, 409 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 846 g

ISBN: 978-1-4020-6713-6
Verlag: Springer Netherlands


Mitochondrial Medicine is a relatively new area where several disciplines from basic science to clinical medicine converge. Mitochondrial medicine deals with diseases that are related to mitochondrial dysfunction due to a number of causes from free radical damage to genetic mutation. A primary feature of mitochondrial dysfunction is impaired cellular bioenergetics.

This book is based upon extensive data gathered over 30 years of clinical and experimental research. Internationally recognized authors share their experience and state-of-the-art knowledge in various fields of their expertise such as mitochondrial cardiology, neurology, diabetology, nephrology, immunology, rheumatology, reproductive medicine, sports medicine, and chronobiology, and guide readers through the disease process, from basic biochemical mechanisms to diagnosis to therapeutic aspects.

Laboratory evaluation plays a very important role in the diagnosis of mitochondrial diseases, in addition to clinical assessment. This includes analysis of plasma/mitochondrial coenzyme Q content, mitochondrial respiratory chain function and oxidative phosphorylation in isolated mitochondria and biopsy material, and nuclear magnetic resonance methods.

In addition to standard medical therapy to treat cardiac, CNS, and other involvements in the mitochondrial disease patients, adjunctive nutritional therapy is indicated primarily to improve mitochondrial function. Therapy include coenzyme Q, a -lipoic acid, carnitine, w -3- and w -6-PUFA, vitamins and polarized light.

Mitochondrial Medicine is dedicated to Dr. Frederick L. Crane, discoverer of Coenzyme Q in 1957, and to the Celebration of 50 year of Coenzyme Q discovery.

This book is intended for general medical practitioners, for specialists such as cardiologists, neurologists, and diabetologists, biochemists, nutritionists, pharmacists, and also for graduate students.

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Weitere Infos & Material


Mitochondrial Physiology.- Oxidants, Antioxidants and Oxidative Stress.- Chronobiology, Chronomics and N-of-1 Tests of Timing Coenzyme Q10.- Methods of Chronobiometric Analysis of Mitochondrial Function.- Mitochondrial Medicine.- Mitochondrial Cardiology.- Mitochondria of the Human Transplanted Heart.- Mitochondrial Diabetology.- Mitochondrial Nephrology.- Mitochondrial Bioenergetics of Skeletal Muscles.- Rheumatoid Arthritis.- Mitochondrial Immunology.- Mitochondrial “Spermatopathy”.- Methods for Diagnosis of Mitochondrial Diseases.- Nuclear Magnetic Resonance.- Clinical Aspects of Coenzyme Q10 in Relationship with Its Bioenergetic and Antioxidant Properties.- Coenzyme Q10 Supplementation in Clinical Medicine.- Coenzyme Q10 Supplementation in Experimental Medicine.- Omega-3-PUFA, Omega-6-PUFA and Mitochondria.- Carnitine.- Vitamins in Mitochondrial Function.- Polarized Light.



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