Integrated Microfabricated Biodevices

1. Auflage 2002
ISBN: 978-0-8247-0606-7
Verlag: CRC Press

Buch, Englisch, 464 Seiten, Format (B × H): 158 mm x 239 mm, Gewicht: 726 g

This book discusses the new generation of integrated microfabricated devices, including DNA chips, Lab-on-a-Chip, microcapillary electrophoresis systems, biosensors, and microanalytical systems. It traces their development with the established and evolving technologies such as microlithography, micromachining, microelectromechanical systems, microfluids, and nanotechnology.

Zielgruppe

Professional

Autoren/Hrsg.

Heller, Michael J.

Guttman, Andras

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe
• Naturwissenschaften Chemie Physikalische Chemie
• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik

Inhaltsverzeichnis

Towards integrated electrophoretic microdevice for clinical diagnostics; creating a lab-on-a-chip with microfluidic technologies; Short Tandem Repeat (STR) analysis on microfabricated electrophoretic devices; basic sample preparation - DNA separation and purification; multiplex integrated online sample preparation for DNA sequencing and genetic typing; interfacing capillaries to microseparation devices for sample introduction; electric field meditated separation of DNA fragments on planar gel microchips; development of battery powered, portable instrumentation for rapid PCR analysis; practical aspects of sheath flow fraction collection in CE; microelectric array systems for DNA diagnostic and pharmacogenomic applications; the flowthru chip - a miniature, three-dimensional biochip platform; DNA arrays on plastic devices; microfluidic devices fabricated by polymer hot embossing; microfabricated reactor technology; approaches toward miniaturization of high throughput screening of chemical libraries; integrated microsystems in clinical chemistry - constraints and consequences.

Über Autor(innen)

Michael J. Heller, Andras Guttman