Buch, Englisch, 546 Seiten, Format (B × H): 191 mm x 235 mm, Gewicht: 1040 g
Engineered Microenvironments for Safety and Efficacy Testing
Buch, Englisch, 546 Seiten, Format (B × H): 191 mm x 235 mm, Gewicht: 1040 g
ISBN: 978-0-12-817202-5
Verlag: William Andrew Publishing
Users will learn about the limitations of 2D in-vitro models and the available 3D in-vitro models (what benefits they offer and some examples). Finally, the MOC section shows how the organ on a chip technology can be adapted to improve the physiology of in-vitro models.
Autoren/Hrsg.
Fachgebiete
- Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie Medizinische Biotechnologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe
- Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
- Technische Wissenschaften Elektronik | Nachrichtentechnik Elektronik Elektronische Baugruppen, Elektronische Materialien
- Technische Wissenschaften Maschinenbau | Werkstoffkunde Maschinenbau Mechatronik, Mikrosysteme (MEMS), Nanosysteme
Weitere Infos & Material
1. Need for alternative testing methods and opportunities for organ-on-a-chip systems 2. Cell sources and methods for producing organotypic in vitro human tissue models 3. Organs-on-a-chip engineering
Part I Organ-on-a-chip platforms to model disease pathogenesis 4. Lung-on-a-chip platforms for modeling disease pathogenesis 5. Requirements for designing organ-on-a-chip platforms to model the pathogenesis of liver disease 6. Brain-on-a-chip systems for modeling disease pathogenesis 7. Kidney-on-a-chip 8. Heart-on-a-chip 9. Caenorhabditis elegans-on-a-chip: microfluidic platforms for high-resolution imaging and phenotyping 10. Gut-on-a-chip microphysiological systems for the recapitulation of the gut microenvironment 11. Computational pharmacokinetic modeling of organ-on-chip devices and microphysiological systems
Part II Multi-organs-on-a-chip platforms to mimic humans physiology 12. Design and engineering of multiorgan systems 13. 8.b. Human body-on-a-chip systems 14. Automation and opportunities for industry scale-up of microphysiological systems 15. How to build your multiorgan-on-a-chip system: a case study