Novel Carrier Systems for Targeted and Controlled Drug Delivery

2024
ISBN: 978-981-97-4969-0
Verlag: Springer Nature Singapore

Buch, Englisch, 531 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 978 g

The book presents novel carrier systems for the targeted and controlled drug delivery for the treatment of various diseases which are difficult to be treated with conventional drug delivery systems like cancer, autoimmune disorders, and emerging infectious diseases. It also reviews the origins and applications of stimuli-responsive polymer systems and polymer therapeutics such as polymer-protein and polymer-drug conjugates. The book also explores the potential applications of the parenteral route of administration for the delivery of active pharmaceutical substances with a narrow therapeutic index and poor bioavailability. Further, the book presents common routes of administration for the systemic delivery of peptides and proteins. It also examines the applications of various implantable systems in drug delivery. The book also covers the important colloidal drug delivery systems, including liposomes and niosomes and solid lipid nanoparticles, and nanostructured lipid carriers. Towards,the end, the book discusses the therapeutic potential of biodegradable polymeric nanoparticles for controlled drug delivery. Authoritative and thorough, this book is a valuable resource for researchers working on a multidisciplinary approach to employing drug delivery systems.

Zielgruppe

Research

Autoren/Hrsg.

Jain, Keerti

Yadav, Awesh K.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin

Inhaltsverzeichnis

Chapter 1_Fundamentals of targeted drug delivery.- Chapter 2_Influence of drug properties and routes of drug administration on design of sustained and controlled release systems.- Chapter 3_Polymeric materials in controlled drug delivery.- Chapter 4_Biopharmaceutic and pharmacokinetic aspects of peroral Controlled Drug Delivery Systems.- Chapter 5_Parenteral drug delivery.- Chapter 6_Proteins / peptides drug delivery systems.- Chapter 7_Transdermal / skin drug delivery system.- Chapter 8_Implantable Therapeutics Systems.- Chapter 9_Chemical drug delivery systems.- Chapter 10_Targeted brain delivery.- Chapter 11_Targeted Tumor Delivery.- Chapter 12_Miscellaneous targeting approaches: Fundamentals of gene delivery, Overview of colon, liver, macrophage, mitochondrial and M cells targeting.- Chapter 13_Overview of Specialized drug delivery systems: Transfersomes, Ethosomes, Layersomes, Bilosomes,Emulsomes, Virosomes, Cubosomes, Aquasomes, Pharmacosomes. Dendrimers, Polymeric Micelles and Resealed Erythrocytes.- Chapter 14_Controlled release formulations for alternate routes of administration.- Chapter 15_Stimuli responsive drug delivery systems: Magnetically, thermal and pH-assisted drug delivery systems.- Chapter 16_Role of controlled release in veterinary formulations.- Chapter 17_Colloidal drug delivery systems: (a) Liposomes and niosomes.- Chapter 18_Solid lipid nanoparticles and nanostructured lipid carriers.- Chapter 19_Polymeric nanoparticles – PLGA, chitosan, albumin, gelatin, alginate etc and Carbon nanotubes.- Chapter 20_Theranostics Application of Controlled Release Drug Delivery systems.- Chapter 21_Regulatory approval pathways involved in controlled release formulations.

Über Autor(innen)

Dr. Awesh K. Yadav is currently working as Assistant Professor of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER) – India. Dr. Yadav has completed his B. Pharm, M. Pharm, and Ph.D. degree from Dr. Hari Singh Gour University, Sagar (MP) India. Dr. Yadav served as Principal at Bhagyoday Tirth Pharmacy College Sagar (MP) India.  Earlier, he served as Assistant Manager in R&D (Formulation) at Ipca Laboratories Limited Mumbai India. He has also worked as Research Scientist at Himalaya Drug Company Bangalore, India and as a Research Assistant at Sun Pharm Advanced Research Centre (SPARC), Vadodara (GJ). Dr. Yadav completed three research project funded by SERB, New Delhi, DBT New Delhi and MPCST Bhopal. His research interest is in drug delivery and drug targeting using various drug delivery systems and ligands i.e., Nanoparticles, Nanodiamonds, fullerenes, etc.

He has been conferred with various prestigious awards, notably, the Outstanding Teacher award by APTI MP State Branch, and the Best Cited Paper award by the International Journal of Pharmaceutics (Elsevier Publication). He has served as a reviewer for several international journals, including the International Journal of Pharmaceutics and the International Journal of Biological Macromolecules. International Journal of Nanomedicine etc. He has more than 15 years of teaching experience in Pharmaceutics.

He has more than 100 i.e., 58 research articles, many review articles in peer-reviewed international journals, 34 book chapters in books from national and international publishers and authored or co-authored, and 6 books in national and international publishers. He has also filled 3 patents. He is a member of many international scientific societies and organizations importantly, Association of Pharmaceutical Teachers of India (APTI), Society of ethnopharmacology, Society of Pharmaceutical Education and Research, India.

Dr. Keerti Jain, Assistant Professor, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER) - Raebareli, earned her M. Pharm. and Doctorate degree from Department of Pharmaceutical Sciences, Dr. H. S. Gour Central University, Sagar. She previously worked as Associate Professor in ISF College of Pharmacy, Moga, India and as Assistant Professor in Delhi Pharmaceutical Sciences and Research University (DPSRU), New Delhi.  Dr. Jain did her Post Doctorate from M. S. University of Vadodara, India as SERB-National Post-Doctoral Fellow. She has about 12 years of research experience on Nanomedicine-based drug delivery systems. Dr. Jain has supervised M. Pharm. and Pharm. D. students for their research works which have been published in quality journals with good impact factor. Dr. Jain has filed five patents from her innovative research and received funding for research projects from ICMR and SERB, New Delhi. She has edited books and contributed more than 20 book chapters with international publishers.

She has been awarded with various research fellowships including SERB – NPDF, CSIR-SRF, UGC-JRF and awarded with many awards for her research work including Pharmaceutical Science Alumni Award-2006, most innovative Idea award in LUFTHANSA impact week and prestigious ICMR – Shakuntala Amir Chand Prize for the year 2019. She has been invited to present her research work at several national and seven international conferences and enlisted among World’s Top 2% Scientists, consecutively for year 2020 and 2021 in the field of Pharmacology & Pharmacy, a list created by Stanford University, USA.