Buch, Englisch, 590 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 1206 g
Buch, Englisch, 590 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 1206 g
ISBN: 978-0-387-77908-9
Verlag: Springer
The immune system reacts vigorously to foreign invaders such as viruses, bacteria, protozoa, and parasites, and yet shows unresponsiveness to our own proteins. In the past decade, several types of T lymphocytes in the immune system have been discovered to function as regulatory cells to suppress unwanted immune responses to self-proteins, leading to the protection of autoimmunity. Furthermore, regulatory T cells also protect us from the development of asthma allergy, and prevent organ transplantation rejection.
“Regulatory T Cells and Clinical Application” provides a comprehensive view of all types of regulatory T cells described so far in the literature. By thoroughly reviewing the immunobiology of regulatory T cells and their implications in various forms of human diseases, a new perspective of therapy using regulatory T cells as individualized medicine to treat inflammatory diseases including diabetes, allergy and transplantation rejection is highlighted.
Zielgruppe
Professional/practitioner
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
Immunobiology of Regulatory T Cells.- Regulatory T Cells and the Control of Auto-Immunity: From day 3 Thymectomy to FoxP3+ Regulatory T Cells.- FoxP3 and Regulatory T Cells.- Thymic and Peripheral Generation of CD4 + Foxp3 + Regulatory T Cells.- The Role of IL-2 in the Development and Peripheral Homeostasis of Naturally Occurring CD4 + CD25 + Foxp3 + Regulatory T Cells.- IL-2 Signaling and CD4+ CD25+ Regulatory T Cells.- TGF-Beta and Regulatory T Cells.- TGF-? Regulates Reciprocal Differentiation of CD4 + CD25 + Foxp3 + Regulatory T Cells and IL-17-Producing Th17 Cells from Naïve CD4 + CD25 – T Cells.- Molecular Signalling in T Regulatory Cells.- Regulatory T Cells in Disease and Clinical Application.- CD4+Foxp3+Regulatory T Cells in Immune Tolerance.- Regulatory T Cell Control of Autoimmune Diabetes and Their Potential Therapeutic Application.- CD4+CD25+ Regulatory T Cells as Adoptive Cell Therapy for Autoimmune Disease and for the Treatment of Graft-Versus-Host Disease.- Natural CD4 + CD25 + Regulatory T Cells in Regulation of Autoimmune Disease.- Multiple Sclerosis and Regulatory T Cells.- CD4+CD25+ Regulatory T Cells and TGF-Beta in Mucosal Inflammation.- Induction of Adaptive CD4+CD25+Foxp3+ Regulatory T Cell Response in Autoimmune Disease.- Regulatory T Cells in Transplantation.- Regulatory T-cells in Therapeutic Transplantation Tolerance.- CD4 + CD25 + Regulatory T Cell Therapy for the Induction of Clinical Transplantation Tolerance.- Regulatory T Cells in Allergic Disease.- Regulatory T Cells and Tumour Immunotherapy.- Regulatory T Cells in Hepatitis and Hepatocellular Carcinoma.- CD4+CD25+ Regulatory T Cells in Viral Infections.- IL-10 and TGF-?-Producing Regulatory T Cells in Infection.- Human Type 1 T Regulatory Cells.- CD8+ T Regulatory Cells inEye Derive Tolerance.- Immune Suppression by a Novel Population of CD8??+TCR??+ Regulatory T cells.- Innate Regulatory iNKT Cells.- Natural Killer T Cells Regulate the Development of Asthma.- The Development, Activation, Function and Mechanisms of Immunosuppressive Double Negative (DN) T Cells.- ?? T Cells in Immunoregulation.
