E-Book, Englisch, 696 Seiten
Kalow / Meyer / Tyndale Pharmacogenomics, Second Edition
2. Auflage 2005
ISBN: 978-0-8493-5950-7
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)
E-Book, Englisch, 696 Seiten
Reihe: Drugs and the Pharmaceutical Sciences
ISBN: 978-0-8493-5950-7
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)
Reflecting the shift from genetics to genomics in the pharmaceutical sphere, this Second Edition traces the evolution of the science of pharmacogenetics and gathers research from the forefront of the field-spanning the most influential breakthroughs in molecular diagnostics, metabonomics, proteomics, bioinformatics, disease mapping, pharmacodynamics, and disease gene identification.
Zielgruppe
Pharmaceutical scientists and biotechnologists; pharmacologists; medical geneticists and pharmacogeneticists; molecular and cell biologists and biochemists; microbiologists and toxicologists; neurobiologists, neuroscientists, and neurochemists; and medical and graduate students in these disciplines.
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
Introduction. Historical Aspects of Pharmacogenetics. Pharmacogenomics and the Promise of Personalized Medicine. Current Status of Pharmacogenomics. Drug Metabolism. Receptors. Pharmacogenetics and Drug Transporters. Variability of Induction Processes. Pharmacogenetics and Cardiac Ion Channels. Interethnic Differences in Drug Response. Clinical Viewpoints. Regulatory Perceptions. Methodologies in Genetics and Genomics. Tools of the Trade: The Technologies and Challenges of Pharmacogenomics. Technologies for the Analysis of Single Nucleotide Polymorphisms. Molecular Diagnostics and Development of Biotechnology-based Diagnostics. Metabonomics. MALDI-TOF MS: Application in Genomics. Measuring Gene Expression: Transcriptional Insights into Functional Biology. From Genotype to Phenotype. Proteomics. Haplotype Structure. Pharmacoepigenetics: From Basic Epigenetics to Therapeutic Applications. Bioinformatics: Aims and Methodologies of a New Discipline. Internet Rsources. Applied Bioinformatics. Genetics of Common Diseases. Mapping of Disease Loci. Positional Cloning and Disease Gene Identification. Genome Variation Influencing Gene Copy Number and Disease. Conclusions. General Conclusions and Future Directions
