Keynes / Edwards / Peel A Century of Mendelism in Human Genetics

1. Auflage 2004
ISBN: 978-1-134-33036-2
Verlag: CRC Press
Format: EPUB
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 176 Seiten

In 1901 William Bateson, Professor of Biology at Cambridge, published a renewed version of a lecture which he had delivered the year before to the Royal Horticultural Society in London (reprinted in the book as an appendix). In this lecture he recognized the importance of the work completed by Gregor Mendel in 1865, and brought it to the notice of the scientific world. Upon reading Bateson's paper, Archibald Garrod realized the relevance of Mendel's laws to human disease and in 1902 introduced Mendelism to medical genetics.
The first part of A Century of Mendelism in Human Genetics takes a historical perspective of the first 50 years of Mendelism, including the bitter argument between the Mendelians and the biometricians. The second part discusses human genetics since 1950, ending with a final chapter examining genetics and the future of medicine. The book considers the genetics of both single-gene and complex diseases, human cancer genetics, genetic linkage, and natural selection in human populations.
Besides being of general medical significance, this book will be of particular interest to departments of genetics and of medical genetics, as well as to historians of science and medicine.

Zielgruppe

Researchers in genetics and medical historians

Autoren/Hrsg.

Keynes, Milo

Edwards, A. W. F.

Peel, Robert

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Geschichte der Medizin

Inhaltsverzeichnis

THE FIRST FIFTY YEARS OF MENDELISM
The Introduction of Mendelism into Human Genetics
Galton’s Theory of Ancestral Inheritance
The Reception of Mendelism by the Biometricians and the Early Mendelians
Mendelism and Man 1918 – 1939
The Darwin Lecture: William Bateson, Archibald Garrod and the Nature of the “Inborn”
HUMAN GENETICS FROM 1950
Linkage and Allelic Association
Malaria and Darwinian Selection in Human Populations
Chromosomal Genetics and Evolution
Mendelian Disorders in Man: The Development of Human Genetics
The Genetics of Complex Diseases
Human Cancer Genetics
Genetics and the Future of Medicine
APPENDIX