Cardiac Drug Therapy

7., th Auflage 2007
ISBN: 978-1-58829-904-8
Verlag: Humana Press

Buch, Englisch, 420 Seiten, GB, Format (B × H): 178 mm x 254 mm, Gewicht: 1008 g

Reihe: Contemporary Cardiology

This book addresses the pharmacology and therapeutic application of drugs used to treat heart diseases and hypertension. Additions and updates to the sixth edition include six new chapters on current controversies in cardiac drug therapy such as the beta blocker issue many cardiologists are presently grappling with. The book provides practical advice on how to manage cardiac diseases and addresses the choice of one particular cardiac agent vs. another.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Khan, M. Gabriel

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Kardiologie, Angiologie, Phlebologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakotherapie, Psychopharmakotherapie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie

Inhaltsverzeichnis

CONTENTS

1 Beta-Blockers: The Cornerstone of Cardiac
Drug Therapy
NEW CONCEPTS
BETA-RECEPTORS
MECHANISM OF ACTION
DOSAGE CONSIDERATIONS
PHARMACOLOGIC PROPERTIES AND CLINICAL IMPLICATIONS
SALUTARY EFFECTS OF BETA-ADRENERGIC BLOCKADE
BETA BLOCKERS VS CALCIUM ANTAGONISTS /NITRATES
INDICATIONS FOR BETA-BLOCKERS
ADVICE AND ADVERSE EFFECTS
INDIVIDUAL BETA BLOCKERS
WHICH BETA-BLOCKER TO CHOOSE



Please LIST HEADINGS for all chapters

2. Beta blocker Controversies
1
3 Angiotensin-converting Enzyme Inhibitors and
Angiotensin II Receptor Blockers 53
Mechanism of Action, 55
ACE Inhibitors Versus Other Vasodilators, 57
Clinical Indications, 59
Contraindications, 64
Advice, Adverse Effects, Interactions, 65
Individual ACE Inhibitors, 67
Angiotensin II Receptor Blockers, 75

4. ACE Inhibitors Controversies

5 Calcium Antagonists (Calcium Channel
Blockers) 81
Mechanism of Action, 81
Major Calcium Antagonists, 83
When to Choose a Calcium Antagonist, 93
Indications for Calcium Antagonists in the New Millennium, 94
Which Calcium Antagonist to Choose, 96
Combination of Calcium Antagonists with Beta-Blockers,
Nitrates, or Digoxin, 98

6. Calcium Antagonists Controversies

7 Diuretics 103
Indications, 105
Thiazides, 106
Loop Diuretics, 106
Potassium-Sparing Diuretics, 112
Other Diuretics, 117


Potassium Chloride Supplements, 118
Important New Information from Clinical Trials, 123

8 Hypertension
new headings to be up dated 127
Relevant Key Issues, 127
Definitions, 130
Nondrug Therapy, 133
Laboratory Work-Up, 134
Which Drugs to Choose, 134
Beta-Blockers, 148
Diuretics, 150
ACE Inhibitors and Angiotensin II Receptor Blockers, 155
Calcium Antagonists (Extended Release), 160
Centrally Acting Drugs, 163
Alpha1-Blockers, 164
Hypertensive Crisis, 166

9. Hypertension Controversies

10 Management of Angina 179
Salient Clinical Features, 179
Treatment of Stable Angina, 180
Management of Unstable Angina, 194
Variant Angina (Prinzmetal's), 201
Recommendations, 203
11 Management of Acute Myocardial
Infarction 209
New Terminology, 209
Therapeutic Implications, 209
Coronary Care Therapeutics, 216
Limitation of Infarct Size and Increased Survival, 221
Thrombolytic Therapy, 222
Beta-Blockers, 233
Nitrates, 235
Ace Inhibitors, 236
Statins, 237
Magnesium, 237
Management of Complications of Infarction, 238
Management of Non-ST-Elevation Myocardial Infarction, 248

12 Management of Heart Failure

new headings to add 255
The Size of the Problem, 255
Diagnosis, 258
Basic Cause, 261
Factors Precipitating Heart Failure, 262
Pathophysiology, 263
Vasodilators, 265
Diuretics, 270
Beta-Blockers, 272


Inotropic Agents, 275
Drug Treatment of Systolic Heart Failure, 287 Management of Diastolic Heart Failure, 293 Management of Pulmonary Edema, 294

13. Heart Failure Controversies

14 Management of Cardiac Arrhythmias delete page numbers 301
Classification, 302
Diagnosis of Arrhythmias, 306
Management of Supraventricular Arrhythmias, 309
Ventricular Arrhythmias, 322
Ventricular Tachycardia, 324
Antiarrhythmic Agents, 328
Class IA, 328
Class IB, 333
Class IC, 337
Class II, 340
Class III, 342
15 Cardiac Arrest

new headings 353
16 Management of Infective Endocarditis 375