Knottnerus / Buntinx | The Evidence Base of Clinical Diagnosis | E-Book | sack.de
E-Book

E-Book, Englisch, 320 Seiten, E-Book

Reihe: Evidence-Based Medicine

Knottnerus / Buntinx The Evidence Base of Clinical Diagnosis

Theory and Methods of Diagnostic Research
2. Auflage 2011
ISBN: 978-1-4443-6063-9
Verlag: John Wiley & Sons
Format: EPUB
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

Theory and Methods of Diagnostic Research

E-Book, Englisch, 320 Seiten, E-Book

Reihe: Evidence-Based Medicine

ISBN: 978-1-4443-6063-9
Verlag: John Wiley & Sons
Format: EPUB
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)



This unique book presents a framework for the strategy andmethodology of diagnostic research, in relation to its relevancefor practice. Now in its second edition The Evidence Base ofClinical Diagnosis has been fully revised and extended with newchapters covering the STARD guidelines (STAndards for the Reportingof Diagnostic accuracy studies) and the multivariable analysis ofdiagnostic data.
With contributions from leading international experts inevidence-based medicine, this book is an indispensable guide on howto conduct and interpret studies in clinical diagnosis. It willserve as a valuable resource for all investigators who want toembark on diagnostic research and for clinicians, practitioners andstudents who want to learn more about its principles and therelevant methodological options available.

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Weitere Infos & Material


List of Contributors, vii
Preface, xi
1 General introduction: evaluation of diagnostic procedures,1
J. Andre Knottnerus, Frank Buntinx, and Chris van Weel
2 The architecture of diagnostic research, 20
R. Brian Haynes and John J. You
3 Assessment of the accuracy of diagnostic tests: thecross-sectional study, 42
J. Andre Knottnerus and Jean W. Muris
4 Diagnostic testing and prognosis: the randomized controlledtrial in test evaluation research, 63
Jeroen G. Lijmer and Patrick M. M. Bossuyt
5 The diagnostic before-after study to assess clinicalimpact, 83
J. Andre Knottnerus, Geert-Jan Dinant, and Onno P. VanSchayck
6 Designing studies to ensure that estimates of test accuracywill travel, 96
Les M. Irwig, Patrick M. M. Bossuyt, Paul P. Glasziou,Constantine Gatsonis, and Jeroen G. Lijmer
7 Analysis of data on the accuracy of diagnostic tests,118
J. Dik F. Habbema, Rene Eijkemans, Pieta Krijnen, and J. AndreKnottnerus
8 Multivariable analysis in diagnostic accuracy studies: whatare the possibilities?, 146
Frank Buntinx, Bert Aertgeerts, Marc Aerts, Rudi Bruyninckx, J.Andre Knottnerus, Ann van den Bruel, and Jef van den Ende
9 Standards for reporting on diagnostic accuracy studies,167
Patrick M. M. Bossuyt and Nynke Smidt
10 Guidelines for conducting systematic reviews of studiesevaluating the accuracy of diagnostic tests, 180
Frank Buntinx, Bert Aertgeerts, and Petra Macaskill
11 Producing and using clinical prediction rules, 213
Tom Fahey and Johan van der Lei
12 Clinical problem solving and diagnostic decision making: aselective review of the cognitive research literature, 237
Alan Schwartz and Arthur S. Elstein
13 Improving test ordering and its diagnostic cost-effectivenessin clinical practice--bridging the gap between clinicalresearch and routine health care, 256
Ron Winkens, Trudy van der Weijden, Hans Severens, and Geert-JanDinant
14 Epilogue: overview of evaluation strategy and challenges,273
J. Andre Knottnerus, Ann van den Bruel, and FrankBuntinx
Index, 285


Andre Knottnerus, Professor of General Practice,Maastricht University. He is involved in the Cochrane movement fordrawing up tools for accurate diagnostic testing
Frank Buntinx, Professor, Department of Public Health,Leuven University. He is one time chair of the CochraneCollaboration Diagnostic and Screening Tests Working Group



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