Reproductive and Developmental Toxicology

1. Auflage 1998
ISBN: 978-0-8247-9857-4
Verlag: CRC Press

Buch, Englisch, 738 Seiten, Format (B × H): 183 mm x 260 mm, Gewicht: 1562 g

This timely resource offers extensive discussions on the pharmacological, environmental,endocrinological, and natural factors that alter reproductive or developmental processes-elucidating the effects of toxicants on mechanisms of reproduction.
Describing biological actions common to both genders as well as gender-specific processes, Reproductive and Developmental Toxicology
- provides an overview of the basic biology and physiology of organ systems affected by toxicants

- furnishes detailed examples of developmental toxicology

- analyzes germ cell toxicity and infertility

- covers the developmental effects of neurotoxicity

- considers periods of exposure and long-term toxicological consequences

- explains how gonadal processes may be susceptible to toxicants in other reproductive organ systems

- and more!
With over 3700 bibliographic citations and more than 100 photographs, drawings, and tables, Reproductive and Developmental Toxicology is a useful reference for toxicologists; reproductive, developmental, cell, and molecular biologists; endocrinologists; biochemists; obstetricians/gynecologists; pediatricians; pharmacists and pharmacologists; physiologists; geneticists; poison control specialists; and upper-level undergraduate, graduate, and medical school students in these disciplines.

Autoren/Hrsg.

Korach, Kenneth S

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Reproduktionsmedizin
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Gynäkologie, Geburtshilfe
• Naturwissenschaften Biowissenschaften Toxikologie

Inhaltsverzeichnis

Development and Neurotoxicity

Müllerian-Inhibiting Substance Activity and Normal Male Sex Determination, David T. MacLaughlin and Patricia K. Donahoe
Effect of Environmental Chemicals on Early Development, Rama S. Dwivedi and Philip M. Iannaccone
Developmental Toxicology, John M. Rogers and Robert J. Kavlock
Malformations in Pregastrulation Developmental Toxicology, Joe C. Rutledge and Walderico M. Generoso
Developmental Effects of Dioxins, Linda S. Birnbaum
Transgenic and Knockout Mice: Genetic Models for Environmental Stress, Robert S. Tebbs, Jack B. Bishop, and Roger A. Pedersen
Genes and Reproductive Behavior Resulting from Normal or Abnormal Development, Sonoko Ogawa and Donald W. Pfaff
Reproductive Neuroendocrine Regulation in the Female: Toward a Neurochemical Mechanism for the Preovulatory Luteinizing Hormone Surge, William R. Crowley
The Hypothalamus and Pituitary as Targets for Reproductive Toxicants, Ralph L. Cooper, Jerome M. Goldman, and Lee Tyrey
Developmental Neurotoxicology, Gaylia Jean Harry
Lead Neuroendocrine Toxicology, Rebecca Z. Sokol

Female Reproduction

Female Reproduction and Toxicology of Estrogens, James H. Clark
Phytoestrogens and Reproductive Medicine, Claude L. Hughes, Jr., and Ginger Tansey
Human Health and Phytoestrogens, Herman Adlercreutz Ovarian Toxicants: Multiple Mechanisms of Action, Barbara J. Davis and Jerrold J. Heindel
Toxicology of Early Pregnancy, Implantation, and Uterine Function, Audrey M. Cummings
TCDD and Uterine Function, Kimberly Silvers and Ellen A. Rorke
Antiestrogenic Activity of TCDD and Related Compounds, Timothy Zacharewski and Stephen H. Safe
Reproductive and Developmental Toxicity of Metals: Issues for Consideration in Human Health Risk Assessments, Rafael A. Ponce and Elaine M. Faustman

Male Reproduction

The Biology of the Male Reproductive Tract, Michael J. McPhaul
Reciprocal Mesenchymal-Epithelial Interactions in Development of the Male Urogenital Tract, Gerald R. Cunha, Annemarie A. Donjacour, and Simon W. Hayward
Influence of Estrogenic Agents on Mammalian Male Reproductive Tract Development, Retha R. Newbold
Toxicity of the Male Excurrent Ducts and Accessory Sex Glands, Gary R. Klinefelter and Rex A. Hess
Developmental Male Reproductive Toxicology of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and PCBs, Beth L. Roman and Richard E. Peterson
Toxicity to Spermatogenesis and Its Detection, Richard M. Sharpe
Gamete Toxicology: The Impact of New Technologies, Sally D. Perreault
Sertoli Cell Toxicants, Ling-Hong Li and Jerrold J. Heindel

Über Autor(innen)

Kenneth S. Korach, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.