Korting / Schafer-Korting The Benefit/Risk Ratio

A Handbook for the Rational Use of Potentially Hazardous Drugs
1. Auflage 1998
ISBN: 978-1-4398-0591-6
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 400 Seiten

The use of drugs as remedies for various types of diseases has a long tradition; however, it has only been recently recognized that the value of any given compound must be evaluated in light of its benefit to risk ratio. When prescribing drugs, physicians must look at the big picture of the drug's benefits in relation to its side effects and possible toxicity. The aim of this handbook is to compile data from various authors, providing clinicians with data that will optimize their decision making in selecting effective, low-risk drug treatments. It also provides research workers, including physicians, pharmacists, and basic scientists, with a sound basis for increasing knowledge of the risk/benefit ratios of various drugs.
Includes detailed assessments of the following types of drugs:

- Antihypertensive agents

- Diuretics

- Anti-diabetic drugs

- Anticonvulsant drugs

- Drugs for Parkinson's disease

- Antihistamines and antiserotonins

- Cytokines and immunomodulators

- Non-opioid analgesics and anti-inflammatory agents

- Antibacterial agents

- Antiviral agents

- Drugs used in reproductive endocrinology

- Systemic drugs for skin diseases

- Topical liposome drugs

- Topical glucocorticoids

Zielgruppe

<li>Pharmacologists
</li><li>Pharmaceutical scientists
</li><li>Toxicologists
</li><li>Physicians
</li><li>Basic scientists</li>

Autoren/Hrsg.

Korting, Hans C.

Schafer-Korting, M.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Naturwissenschaften Biowissenschaften Toxikologie

Inhaltsverzeichnis

The Role and Analysis of Benefit and Risk in the Development of New Drugs, C. Chuang-Stein
Prediction of the Benefit/Risk Ratio from In Vitro Data, R. Shrivastava, C. Bonnabry, and G. John
Evaluation of Therapeutic Benefits and Toxicological Risks Using Structure-Activity Relational Expert Systems, H.S. Rosenkranz, G. Klopman, and O.T. Macina
Improving the Therapeutic Index Through Unusual Routes of Application: Intra-Arterial Treatment of Liver Metastases, D. Civalleri, G. Numico, F. DeCian, and M. Esposito
Establishing the Benefit/Risk Ratio with Combination Drugs, A. Thürmann and J. Hasford
Improving the Therapeutic Index of Antineoplastic Agents through Additional Drugs, G. Numico, D. Civalleri, and M. Esposito
Antihypertensive Agents, B. Schwartzkopff and B.E. Strauer
Diuretics, J. Zhi
Anti-Diabetic Drugs, P. Compagnucci and F. Santeusanio
Anticonvulsant Drugs and Drugs for Parkinson's Disease, M.J. Eadie
Antihistamines and Antiserotonins, G. Passalcqua and G.W. Canonica
Cytokines and Immunomodulators, D.J. Peace, W. Wong, and K.T. Ferrer
Non-Opioid Analgesics and Anti-Inflammatory Agents, G. Traversa and N. Magrini
Toxicity Profile of Liposomal Anthracyclines, A. A. Gabizon
Antibacterial Agents, R. Garraffo
Antiviral Agents, J.M. Kilby
Antifungal Agents, A.K. Gupta, P. De Doneker, and M. Heenen
Drugs Used in Reproductive Endocrinology, J.F. Mortola
Nicotine Preparations in Smoking, N.L. Benowitz and J. Pinney
Systemic Drugs for Skin Diseases, H. Bocquet, L. Le Cleach, and J.-C. Roujeau
Topical Liposome Drugs, H.C. Korting
Topical Glucocorticoids, M. Schäfer-Korting and A. Gysler
Index