Kroening / Easter / Richardson Analysis of Chemical Warfare Degradation Products

1. Auflage 2016
ISBN: 978-1-119-97019-4
Verlag: John Wiley & Sons
Format: EPUB
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 168 Seiten, E-Book

This book describes nerve agents and vesicants, their decomposition and their degradation products' chemistry as well as their toxicity including a list of detection techniques of nerve agents and their degradation products. This book will present their history, toxicity, comparison between different sample preparation methods, separation techniques, and detection methods all together in a short, easy to read book, tied together by a single group doing the writing and the editing to assure smooth transition from chapter to chapter, with sufficient Tables and literature references for the reader who looks to further detail.The text will illustrate the pluses and minuses of the various techniques with sufficient references for the reader to obtain extensive detail.

Autoren/Hrsg.

Kroening, Karolin K.

Easter, Renee N.

Richardson, Douglas D.

Willison, Stuart A.

Caruso, Joseph A.

Inhaltsverzeichnis

Preface.
1 Historical Milieu.
1.1 Organophosphorus Nerve Agents.
1.2 Blister Agents.
1.3 Sternutator Agents.
1.4 Chemical Weapons Convention (CWC).
1.4.1 Schedule of Chemicals.
1.4.2 Destruction of Chemical Weapons.
References.
2 Toxicity of Chemical Warfare Agents and their DegradationProducts.
2.1 Organophosphorus Nerve Agent Toxicity.
2.1.1 Toxicity Mechanism - AcetylcholinesteraseInhibition.
2.1.2 Exposure.
2.1.3 Response, Treatment and Prevention.
2.2 Toxicity of Nerve Agent Degradation Products.
2.2.1 Toxicity of GA (Tabun) Degradation Products.
2.2.2 Toxicity of GB (Sarin) Degradation Products.
2.2.3 Toxicity of GD (Soman) Degradation Products.
2.2.4 Toxicity of GF (Cyclosarin) Degradation Products.
2.2.5 Toxicity of VX Degradation Products.
2.3 Toxicity of Blister Agents.
2.4 Toxicity of Sternutator Agents.
2.4.1 Toxicity of Degradation Products of SternutatorAgents.
References.
3 Analysis of Chemical Warfare Agents.
3.1 Introduction.
3.2 Minimally Invasive Detection Techniques.
3.3 Separation and Detection Techniques.
3.3.1 Capillary Electrophoresis.
3.3.2 Ion Mobility Spectrometry.
3.3.3 Gas Chromatography (GC)/Gas Chromatography-MassSpectrometry (GC-MS).
3.3.4 Liquid Chromatography (LC)/Liquid Chromatography-MassSpectrometry (LC-MS).
3.3.5 Desorption Electrospray Ionization and Direct Analysis inReal Time Mass Spectrometry.
References.
4 Chemical Warfare Agent Degradation Products.
4.1 Analysis of Nerve Agent Degradation Products.
4.1.1 Sample Preparation.
4.1.2 Liquid-Liquid Extraction (Pre-concentration).
4.1.3 Solid Phase Extraction (SPE).
4.1.4 Solid Phase Microextraction (SPME).
4.1.5 Stir Bar Sorptive Extraction (SBSE).
4.1.6 Derivatization.
4.2 Analytical Techniques.
4.2.1 Gas Chromatography (GC).
4.2.2 Liquid Chromatography (LC).
4.2.3 Elemental Speciation.
4.2.4 Ion Mobility.
4.2.5 Capillary Electrophoresis.
4.3 Analysis of Sulfur Mustard Degradation Products.
4.4 Analysis of Sternutator Degradation Products.
References.
Appendix.
Index.