Diabetes and Alzheimer's Disease

Mechanisms and Management
Erscheinungsjahr 2025
ISBN: 978-0-443-40559-4
Verlag: Elsevier Science

Buch, Englisch, 450 Seiten, Format (B × H): 191 mm x 235 mm

Diabetes and Alzheimer's Disease: Mechanisms and Management explores the intricate relationship between diabetes and Alzheimer’s disease, exploring how these conditions intersect and influence each other. The book introduces the confluence of both diseases; and their pathophysiological and epidemiological aspects. The book provides deep insights into metabolic interactions and molecular signaling regulating the confluence of these diseases and discusses various factors influencing it. In addition, theranostics and strategies are presented to manage the conditions through drug repositioning and dietary modifications are also discussed in depth. The insights from this book will help readers understand the interconnections and cross talks between metabolic dysfunction like diabetes to neurological disorder like Alzheimer’s disease. Written by experts in the field for researchers, academicians, scientists and graduate students in the field of biomedical and pharmaceutical sciences.

Autoren/Hrsg.

Kumar, Awanish

T R, Anju

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften

Inhaltsverzeichnis

1. Introduction to Confluence of Diabetes and Alzheimer's Disease
2. Epidemiology related to Diabetes and Alzheimer's Disease
3. Pathophysiology of Diabetes and Alzheimer's Disease
4. Metabolic Relationship and Crosstalk in Diabetes and Alzheimer's Disease
5. Insulin Signaling in Diabetes and Alzheimer's Disease
6. Epigenetic Insight of Alzheimer's Disease and Diabetes
7. Inflammation in Alzheimer's Disease and Diabetes
8. Possible impact of Co-occurrence of Alzheimer's Disease and Diabetes
9. Impact of Oxidative Stress on Diabetes and Alzheimer's Disease
10. Cognitive Dysfunction: Link between Diabetes and Alzheimer's Disease
11. Theronostics in Alzheimer's Disease and Diabetes
12. Drug Repositioning Strategies of Anti-diabetic Drugs for Alzheimer's Disease
13. Nutritional Aspect and Management of Alzheimer's Disease and Diabetes

Über Autor(innen)

T R, Anju
Dr. Anju T R is Assistant Professor Biotechnology at Newman College, Kerala and Secretary of Society for Biotechnologists. She completed her Masters degree in Biotechnology at Gulbarga University, Karnataka, India and doctoral degree at Centre for Neuroscience, Cochin University of Science and Technology, Kochi, India. Dr. Anju completed her postdoctoral research on a five year project funded by Department of Biotechnology to study the long term effects of neonatal hypoglycemia. She has published 44 research papers in SCI journals; 19 book chapters and edited 7 books and is the recipient of Kerala State Young Scientist Award 2012 by Kerala State Council for Science, Technology and Environment; and various other awards. Her research is focused on molecular signaling and neurotransmitter receptor functions in the brain under neonatal stress and various disease conditions like diabetes and epilepsy. Currently her research team is working on nanotechnology and phyto-constituent based interventions for biomedical applications.

Kumar, Awanish
Dr. Awanish Kumar is currently an Associate Professor in the Department of Biotechnology at the National Institute of Technology, Raipur (CG), India. He has more than 13 years of research experience. He received his PhD in Molecular Parasitology from the CSIR-Central Drug Research Institute, Lucknow, India, and Jawaharlal Nehru University, Delhi, India, and completed his postdoctoral studies at McGill University, Montreal, Canada. His research interests are infection biology, drug targeting, and drug discovery. Dr. Kumar has served on various national and international organizations in different academic and research capacities. He has also served on many national committees and scientific advisory panels, as a member of many international professional research societies, and as a reviewer and editorial board member of reputed and refereed journals. He has authored or edited several monographs, books, and book chapters.