Buch, Englisch, 86 Seiten, Format (B × H): 237 mm x 160 mm, Gewicht: 296 g
Techniques for Structural Characterization of Glycans
Buch, Englisch, 86 Seiten, Format (B × H): 237 mm x 160 mm, Gewicht: 296 g
ISBN: 978-0-12-804129-1
Verlag: Elsevier Science Publishing Co Inc
Mass Spectrometry: Techniques for the Structural Characterization of Glycans presents new methods for conducting detailed carbohydrate qualitative analysis-arming analytical chemists, pharmaceutical scientists, and food scientists with a quick reference that will allow them to determine the structures of carbohydrates molecules.
As there is a need in the scientific community for content specific to structural determination and analysis of new glycoprotein drug, and because structure-activity analysis requires a structural determination of the N- and O-linked oligosaccharides linked to glycol-proteins, this book provides the relevant research that are necessary for advances and new outcomes in this area of study.
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
. Introduction. Monosaccharide Composition Analysis. Elemental Analysis of MS Ions. Derivatization Techniques. Hydride Addition to Sulfate and phosphate- Chemistry. InstrumentationMALDI-TOF MSAPI 2000 MSICP ESI TOF MS. Hydride Insertion Addition Reaction for the Derivatization of Phosphorylated or Sulfated Glycans and the Discernment of Phosphate versus Sulfate Esters. Ester Substitution MS MethodThe Protocol for the Hydride Addition to the ethanol extract of banana fruitExample of MS2on Hydride added to the ethanol Extract of Banana Fruit Glycan. Glycan Isolation Methods. Other Glycan isolation Methods. Monosaccharide AnalysisAcid Hydrolysis. Mass Spectral Carbohydrate Structure Determination MethodMSMS/MS (MS2)MSnProposing Initial Structure Refining Methods for Determining Exact Mass StructureMS Instrumentation Requirements for Discovering Whole Molecule IonsDerivatization Method and Sulfate/Phosphate Discernment Method. References
