McPherson Introduction to Macromolecular Crystallography

2. Auflage 2011
ISBN: 978-1-118-21063-5
Verlag: John Wiley & Sons
Format: EPUB
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 280 Seiten, E-Book

A comprehensive and approachable introduction to crystallography-- now updated in a valuable new edition
The Second Edition of this well-received book continues to offerthe most concise, authoritative, and easy-to-follow introduction tothe field of crystallography. Dedicated to providing a complete,basic presentation of the subject that does not assume a backgroundin physics or math, the book's content flows logically from basicprinciples to methods, such as those for solving phase problems,interpretation of Patterson maps and the difference Fourier method,the fundamental theory of diffraction and the properties ofcrystals, and applications in determining macromolecularstructure.
This new edition includes a vast amount of carefully updatedmaterials, as well as two completely new chapters on recording andcompiling X-ray data and growing crystals of proteins and othermacromolecules.
Richly illustrated throughout to clarify difficult concepts,this book takes a non-technical approach to crystallography that isideal for professionals and graduate students in structuralbiology, biophysics, biochemistry, and molecular biology who arestudying the subject for the first time.

Autoren/Hrsg.

McPherson, Alexander

Inhaltsverzeichnis

PREFACE.
1. AN OVERVIEW OF MAROMOLECUEAR CYRSTALLOGRAPHY.
2. CRYSTALLIZATRION OF MACROMOLEUCLES.
3. THE NATURE OF CRYSTALS: SYSMMETRY AND THE UNIT CELL.
4. WAVES AND THEIR PROPERTIES.
5. DIFFRACTION FROM POINTS, PLANES, MOLECULES, AND CRYSTALS.
6. INTERPRETATIN OF DIFFRACTION PATTERNS.
7. DATA COLLECTION.
8. SOLVING THE PHASE PROBLEM.
9. INTERPRETING PATTERSON MAPS.
10. ELECTRON DENSITY, REFINEMENT, AND DIFFERENCE FOURIERMAPS.
BIBLIOGRAPHY.
INDEX.

Über Autor(innen)

Alexander Mcpherson, PhD, is Professor in the Department of Molecular Biology and Biochemistry at the University of California, Irvine's School of Biological Sciences. The author of six books and 300 papers or reviews, he is widely considered the nation's foremost authority in the field of macromolecular crystallography. For over a decade, he has served as principal instructor of the Cold Spring Harbor Laboratory course inmacromolecular X-ray crystallography, an intensive course for which much of the material in this text was originally conceived.