Biomaterials for Advanced Drug and Therapeutics Delivery

Erscheinungsjahr 2025
ISBN: 978-0-443-26657-7
Verlag: Elsevier Science

Buch, Englisch, 700 Seiten, Format (B × H): 152 mm x 229 mm

Biomaterials for Advanced Drug and Therapeutic Delivery provides a detailed review of a range of biomaterials for drug delivery, gene, vaccine and therapeutics delivery, and wound healing and tissue regeneration. Divided into 5 sections, this book begins with an introduction to biomaterials for biomedical applications before systematically detailing advances in each application. A wide selection of biomaterials are covered, including nanobiomaterials, biopolymers, hydroxyapatite, lipid-based biomaterials, proteins, and more. In addition, the properties and characteristics of each biomaterial type is assessed, along with it’s suitability for a range of drug delivery and therapeutic applications.

The final section of the book provides insight into the safety, biocompatibility, preclinical and regulatory aspects of biomaterials use, exploring the translational potential of these novel materials and treatments. This book will be of use to researchers and academics in the fields of materials science, biomaterials, pharmaceutical science, and regenerative medicine.

Autoren/Hrsg.

Mohd Amin, Mohd Cairul Iqbal

Greish, Khaled

Fachgebiete

• Technische Wissenschaften Maschinenbau | Werkstoffkunde Technische Mechanik | Werkstoffkunde
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie
• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe

Inhaltsverzeichnis

SECTION 1: BIOMATERIALS - AN OVERVIEW

1. Overview of biomaterials in biomedical applications

SECTION 2: BIOMATERIALS FOR DRUG DELIVERY
1. Medium chain triglycerides and fractions in drug delivery systems
2. Nanostructured lipid carrier phytoconstituents delivery
3. Aloe vera in topical and transdermal drug delivery systems
4. Biomaterials in inhalation and nasal drug delivery
5. Lipid-based cubosomes for modified-release drug delivery
6. Cationic nanoparticles for drug delivery targeting the brain
7. Advances in biomaterials for targeted brain drug delivery
8. Bacterial cellulose composites for drug and protein delivery
9. Hydrogels for drug delivery

SECTION 3: BIOMATERIALS FOR GENE, VACCINE AND THERAPEUTICS DELIVERY
10. Marine-based biopolymers for gene delivery
11. Biomaterials RNAi-, mRNA and DNA-based delivery and therapeutics
12. Biomimetic nanoparticles as vaccine delivery platforms
13. Bacterial cellulose composites for oral vaccine delivery
14. Proteins and peptides for therapeutics
15. Synthetic polymers for therapeutics

SECTION 4: BIOMATERIALS FOR WOUND AND TISSUE REGENERATION
16. Biomaterials in tissue engineering - an introduction
17. PLGA microparticles for wound healing
18. Hydroxyapatite for bone tissue repair and regeneration
19. Alginate biocomposite nanofibers in wound healing and tissue regeneration
20. Nanocellulose biocomposites in wound healing applications
21. Bacterial cellulose composites for cell delivery in wound healing
22. Hydrogels for wound healing

SECTION 5: BIOMATERIALS - SAFETY AND REGULATORY CONSIDERATIONS
23. Zebrafish larvae models: Biomaterials safety for drug delivery
24. Safety, biocompatibility, and preclinical considerations for biomaterials
25. Regulatory considerations for biomaterials in medical applications

Über Autor(innen)

Mohd Amin, Mohd Cairul Iqbal
Dr. Mohd Cairul Iqbal Mohd Amin is a Professor of Pharmaceutics in the Faculty of Pharmacy, Universiti Kebangsaan Malaysia (UKM) in Kuala Lumpur, Malaysia. He is the youngest professor appointed in the faculty and the only expert in the area of pharmaceutics in UKM. He earned his BSc (Hons) in Pharmacy in 1996 and PhD in 2001 both from the University of Manchester, United Kingdom. He is currently the Head of Drug Delivery and Novel Targeting Research Group in UKM. He also serves as panel expert in nanocellulose for drug delivery for the National Nanotechnology Centre, Ministry of Science, Technology and Innovation, Malaysia. His current research interests encompass responsive-hydrogel biomaterials for oral protein and peptide delivery, cell delivery in tissue engineering and nano drug delivery systems in particular polymeric micellar conjugates for cancer research. Dr. Amin has authored more than 60 publications in high impact factor journals, a number of book chapters, has five patents issued/pending and has routinely consulted in the area of drug delivery and pharmaceutical technology. He has wide expertise in biomaterials, nanomedicine, polymer chemistry, micro- and nanotargeting delivery systems as well as oral and transdermal formulations and delivery systems.