MRNA-Based Therapeutics

Erscheinungsjahr 2022
ISBN: 978-0-323-99401-9
Verlag: William Andrew Publishing

Buch, Englisch, 326 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 450 g

MRNA-Based Therapeutics, Volume 372 in the International Review of Cell and Molecular Biology series, covers topics surrounding the effect of different metabolic situations, their contribution to metabolic modulation, and their impact on tumor growth. Specific chapters in this release include New era of nucleic acid therapies: Clinical applications and perspectives, Messenger RNA as personalized therapy: time of truth for rare metabolic disease, Applications of Self-Replicating RNA, mRNA therapy in PKU, Advances in gene-editing technologies, mRNA delivery technologies: towards clinical translation, Advances in mRNA vaccines, and more.

Zielgruppe

Academic, government and industrial sectors

Autoren/Hrsg.

Weitere Mitwirkende

Berraondo, Pedro

Fachgebiete

• Naturwissenschaften Biowissenschaften Entwicklungsbiologie
• Naturwissenschaften Biowissenschaften Zellbiologie
• Naturwissenschaften Biowissenschaften Molekularbiologie

Inhaltsverzeichnis

1. New era of nucleic acid therapies: Clinical applications and perspectives Andoni Garitano 2. Messenger RNA as personalized therapy: time of truth for rare metabolic disease Antonio fontanellas 3. Applications of Self-Replicating RNA Kenneth Lundstrom 4. mRNA therapy in PKU Ramon Diaz Trelles 5. Advances in gene-editing technologies Robert MacLaren and Ruofan Connie Han 6. mRNA delivery technologies: towards clinical translation Maria Angeles Solinis 7. Advances in mRNA vaccines Xiaojun Xia

Über Autor(innen)

Berraondo, Pedro
Pedro Berraondo graduated in Pharmacy at the University of Navarra in 1999. In 2004 he obtained the Ph.D. at the same university. Next, he worked at the Pasteur Institute in Paris (France) under the supervision of Dr. Claude Leclerc, where he developed novel strategies in tumor immunotherapy within the European THERAVAC project. In February 2007, he joined the Immunology and Immunotherapy Program at the Cima Universidad de Navarra, where he leads the Cytokine-based Immunotherapy laboratory. He is co-inventor of ten patents and he is co-author of more than 140 publications, including publications in Nature, Nature Medicine, Nature Reviews Drug Discovery, Immunity, Cancer Discovery, and Cancer Cell. He was certified as a full professor in 2021 by AQU. He is co-director of the degree of expert in immunooncology at the Faculty of Medicine of the University of Navarra, and is in charge of the undergraduate course of macromolecular structure at the Faculty of Sciences of the University of Navarra. He is also the coordinator of the immuno-oncology work module at CIBERONC.